نتایج جستجو برای: opiate substances
تعداد نتایج: 60600 فیلتر نتایج به سال:
Opiates are utilized routinely and effectively as a short-term analgesic treatment for a variety of acute pain conditions such as occur following trauma, and for patients with painful terminal diseases such as cancer. Because opiate analgesics are highly addictive substances, their use in the treatment of chronic nonmalignant pain remains controversial.
Background: Iran is one of the major consumers of opium and opiate substances in the world. Addiction has become a very important issue in the 21st century and an urgent one in Iran. The consumption of this substance leaves a variety of impacts on the human body. The goal of this study is to investigate the changes of the biochemical parameters derived from opiate substances in addicts during t...
Article history: Received 8 June 2015 Accepted 4 February 2016 Available online 11 February 2016 The importance of the GABA-benzodiazepine receptor complex and its subtypes are increasingly recognised in addiction. Using theα1/α5 benzodiazepine receptor PET radioligand [C]Ro15 4513, we previously showed reduced binding in the nucleus accumbens and hippocampus in abstinent alcohol dependence. We...
The importance of the GABA-benzodiazepine receptor complex and its subtypes are increasingly recognised in addiction. Using the α1/α5 benzodiazepine receptor PET radioligand [(11)C]Ro15 4513, we previously showed reduced binding in the nucleus accumbens and hippocampus in abstinent alcohol dependence. We proposed that reduced [(11)C]Ro15 4513 binding in the nucleus accumbens was a marker of add...
Copyright © 2007 LLS SAS. All rights reserved Individual differences in response to addictive substances may provide important clues to the mechanisms underlying drug action, addiction, reward, and reward-related disease states. Early psychoneuroendocrinological studies have led to the distinction of responders and nonresponders upon μ opiate receptor agonist administration. The systematic anal...
Since 1995, Corrections Services Canada (CSC) has conducted randomized urinalysis screening of a minimum of 5% of the federal inmate population on a monthly basis. Urine samples are screened for a broad range of psychoactive substances. The stated purpose of such screening is to reduce substance use in federal jails. Analysis of data provided by CSC for testing between 1994 and 1998 reveals sma...
The narcotic antagonist naloxene, the n-allyl derivative of oxynlorphone, is used widely by anaesthetists to reverse opiate-induced respiratory depression, However, the discovery that there are endogenous opiate-like substances in the central nervous system and other tissues, and that they are involved in regulation of general physiological phenomena, has raised the possibility that naloxone ma...
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