Secondary degeneration occurs commonly in the central nervous system after traumatic injuries and following acute and chronic diseases, including glaucoma. A constellation of mechanisms have been shown to be associated with secondary degeneration including apoptosis, necrosis, autophagy, oxidative stress, excitotoxicity, derangements in ionic homeostasis and calcium influx. Glial cells, such as...

The role of compression factors on the formation of secondary degenerative factors and antiand retrograde parts of the optic nerve in traumatic injuries has not been fully studied. There are several experimental models of such researches. In 2007 Jiang Y [4] proposed a model of traumatic damage to the optic nerve canal using surgical tools. Degeneration occurs in a swelling in the affected nerv...

  Background :There is not any data available about the effect of high bar pressure condition on intracranial pressure. In this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   Methods : Twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. Only one perso...

Glial fibrillary acidic protein (GFAP) is used as a marker of astrocyte response to various central nervous system injuries. In the present study, the effects of chronic ethanol administration on GFAP immunoreactivity were evaluated in astrocytes of the adult optic nerve head. The results demonstrated that ethanol exposure significantly and dramatically increases GFAP immunoreactivity and the n...

We encountered a patient who suffered a head injury that translated to the optic nerves, leading to dramatic unilateral right optic nerve edema. The decedent was a 20-year-old unsecured passenger in a convertible. The car collided with a pickup truck. The patient survived for 8 h. At autopsy, a comminuted skull fracture involving the right frontal bone including the right orbital plate was foun...

the purpose of this study was to investigate magnetic resonance imaging (mri) of the normal feline eyeand optic nerves using t1-weighted and t2-weighted images. a total of 6 healthy female domestic short haircats age 2-2.5 years and weighing 3.2 ± 0.4 kg were selected. magnetic resonance imaging data werecollected using gemsow (philips) at a magnetic field strength of 1.5 t. dorsal, sagittal, a...

background :there is not any data available about the effect of high bar pressure condition on intracranial pressure. in this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   methods : twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. only one person ...

the conclusion that the clinical nature of the inflammation was that of sympathetic cyclitis. I should like to think that Mr. Neame is right and that I was not to blame for retaining the exciting eye too long. I regret that as far as I can ascertain the exciting eye was not examined histologically. We have no pathological department at The West Bromwich Hospital, and send our eyes to The Birmin...

purpose : to report a rare case of large vascularized astrocytoma on optic disc. case report : a 12-year-old boy with history of decreased vision in the left eye since 5-6 months ago was referred to the ocular oncology service at rassoul akram hospital with provisional diagnosis of retinoblastoma. on examination, visual acuity was counting fingers at 50 cm, and a 3+ relative afferent pupillary ...