Abstract This study aimed to obtain the optimum formula of Chlorella milk with D-Optimal Mixture Design and determine consumer preference for formula. research method was divided into formulation response design, hedonic test, analysis, optimization, verification The determined based on highest score taste. Two solutions were obtained, it found that 0.40% + 0.05% vanillin 4.55% sugar most prefe...

Traditional factorial designs for evaluating interactions among chemicals in a mixture may be prohibitive when the number of chemicals is large. Using a mixture of chemicals with a fixed ratio (mixture ray) results in an economical design that allows estimation of additivity or nonadditive interaction for a mixture of interest. This methodology is extended easily to a mixture with a large numbe...

the binary and ternary codes spanned by the rows of the point by block incidence matrices of some 2-designs and their complementary and orthogonal designs are studied. a new method is also introduced to study optimal codes.

The equivalence theorem is the most important of experimental design. For single response, D-optimal continuous design and equal allocation already exist. However, for multiresponse mixture experiments has not been investigated. In this paper, we study problem find that maximize variance function to number response. designs are illustrated by two examples.

Functional foods are in great demand worldwide because of their many health benefits. As milk is a nutrient-dense diet that comprises all vital nutrients, it can be utilized as the primary base to produce variety functional foods. Ginger, cinnamon and pumpkin possess tremendous nutritional therapeutic properties such stimulating digestive system, lowering blood cholesterol levels exhibiting ant...

Paper aims Frequently, researchers try to find a better way allocate assets in order have maximum return and low variability portfolio as diverse possible. This paper apply D-Optimal Design the context of Mixture optimization efficiently select runs proposed experimental design. Originality A new approach optimal weights that maximize returns minimize risk using was used. multi-response problem...

centralizing and using proper transportation facilities cut down costs and traffic. hub facilities concentrate on flows to cause economic advantage of scale and multimodal transportation helps use the advantage of another transporter. a distinctive feature of this paper is proposing a new mathematical formulation for a three-stage p-hub location routing problem with simultaneous pick-ups and de...

The objective of the current study was to develop and optimize a sublingual tablet formulation of captopril which is an effective drug in the treatment of hypertension. Captopril containing tablets were prepared by direct compression method using different ingredients such as polyvinyl pyrrolidone, starch 1500, sodium starch glycolate and lactose (independent variables) and magnesium stearate, ...