from case 2, however, showed a shoulder at pH4.5 due probably to some residual glucosaminidase A and glucosaminidase B activity. The optimum for both glucosaminidase and galactosaminidase activities ofleucocytes from this patient was pH4.5; here a greater proportion of hexosaminidase A and hexosaminidase B remains, masking the C form. The total hexosaminidase activity of these leucocytes was 4 ...

Characterization and extraction of plant secondary metabolites are important in agriculture, pharmaceutical, and food industry. In this regard, the applied analytical methods are mostly costly and time-consuming; therefore, choosing a suitable approach is essential for optimum results and economic suitability. One of the recently considered methods used to characterize new types of materials is...

This paper addresses the problem of identification of hybrid dynamical systems, by focusing the attention on hinging hyperplanes (HHARX) and Wiener piecewise affine (W-PWARX) autoregressive exogenous models. In particular, we provide algorithms based on mixed-integer linear or quadratic programming which are guaranteed to converge to a global optimum. For the special case where switches occur o...

In this paper we explore how we can use technology to help people to stay motivated to do home fitnessing. Two experiments with a total of 48 participants were performed, both deploying a virtual reality in a bicycling task, one focusing of effects of immersion, the other on the intrinsic impact of movement. From the results it becomes apparent that user and technology can cooperate to achieve ...

In this paper we present resource optimization methods for solving efficiently synthesis problems in a constraint-based framework. We obtain a tight lower bound of the problem optimum by adding redundant constraints that take into account the "wastage" in a partial solution. Abstraction through focusing on relevant features permits added interchangeability to deal with equivalent sets of partia...

This paper analyses the consequences of environmental myopia on policy design in a multi-pollutants framework. Focusing on the correlations between aerosols and greenhouse gases, the paper compares abatement and stock targets setting for various cases of environmental myopia. Both cases of lax and stringent regulation, compared to what is socially optimum, may arise. Furthermore, the lax/string...

This paper addresses the problem of identification of hybrid dynamical systems, by focusing the attention on hinging hyperplanes (HHARX) and wiener piecewise affine (W-PWARX) autoregressive exogenous models. In particular, we provide algorithms based on mixed-integer linear or quadratic programming which are guaranteed to converge to a global optimum. We also discuss issues of state-space reali...

We consider an infinitely large population under stabilizing selection and mutation in which the allelic effects determining a polygenic trait vary between loci. We obtain analytical expressions for the stationary genetic variance as a function of the distribution of effects, mutation rate, and selection coefficient. We also study the dynamics of the allele frequencies, focusing on short-term e...

This work focuses on the problem of automatic loop shaping in the context of robust control. More specifically in the framework given by Quantitative Feedback Theory QFT , traditionally the search of an optimum design, a non convex and nonlinear optimization problem, is simplified by linearizing and/or convexifying the problem. In this work, the authors propose a suboptimal solution using a fix...