OBJECTIVE We have previously reported that the absence of thyroid peroxidase antibodies (TPOAb) in Graves' disease (GD) was associated with an increased risk of Graves' ophthalmopathy (GO). This observation raised the possibility that TPOAb could act as a protective factor. However, the presence of thyroid peroxidase (TPO) in the orbit has not been previously reported. The aim of this study was...

PURPOSE To describe the CT findings of orbital cellulitis due to sinusitis. METHODS The records and CT scans of 45 consecutive patients with orbital cellulitis due to sinusitis treated at the Hospital of the Medical School of Ribeirão Preto were analyzed by a radiologist and two orbital surgeons. RESULTS Three major types of CT changes were observed: diffuse fat infiltration, subperiosteal ...

PURPOSE To investigate the results of graded decompression of orbital fat and walls in Graves' orbitopathy (GO) considering the degree of proptosis reduction at surgery and preoperative computed tomography (CT) findings. METHODS This is a retrospective interventional case series. Graded orbital fat and wall decompression was performed in 90 orbits of 55 patients. In patients with enlarged ext...

INFRAORBITAL FAT PAD herniation results in a prominence of the lower eyelids, causing patients to have a tired and aged appearance. These deformities consist of skin, subcutaneous fat, orbicular muscle, and sub orbicular fat. Orbital fat exerts pressure both on the orbital septum and the orbicular muscle, causing a bulge. What appears to be excess skin is often merely the conversity caused by t...

OBJECTIVE To identify and quantify carotenoids found in white and yellow orbital fat. METHODS Specimens of nasal (white) and preaponeurotic (yellow) orbital fat were obtained from patients during upper eyelid blepharoplasty. Carotenoids and retinoids were extracted and subjected to spectral and high-performance liquid chromatography analyses. RESULTS The chromophore content of extracts from...

PURPOSE The purpose of this study is to identify the subgroups of thyroid eye disease (TED) patients most likely to benefit from orbital fat decompression. METHODS This retrospective study reviews 217 orbits of 109 patients who underwent orbital fat decompression for proptosis secondary to thyroid eye disease. Charts were reviewed for demographic, radiographic, clinical, and surgical data. Th...

PURPOSE Little is known about the way orbital fat slides and/or deforms during eye movements. We compared two deformation algorithms from a sequence of MRI volumes to visualize this complex behavior. METHODS Time-dependent deformation data were derived from motion-MRI volumes using Lucas and Kanade Optical Flow (LK3D) and nonrigid registration (B-splines) deformation algorithms. We compared h...

Orbital injury and complications are commonly encountered in endoscopic sinus surgery (ESS) despite advances in techniques and instrumentation. For the recent 10 years, we summarized the experience of the rhinology unit of our department regarding orbital injury and complications of ESS for sinonasal inflammatory disorders. One thousand seventy-three patients (1869 sides) from January 1, 2003 t...

A 30 year old female with absolute glaucoma status post-evisceration developed recurrent orbital implant exposure and scleral melting. We successfully treated the large conjunctiva defect by utilizing secondary implant of dermis fat graft for tissue growth and tension-free conjunctiva closure. The patient was satisfied with the postoperative outcome, and no major complications were observed in ...