Some new Sb(III) and As(III) complexes of N∩S donor ligands N’[1-(2-oxo-2H-chrome-3yl-ethylidene] hydrazinecarbodithionic acid methyl ester (L1H) and N’ [1-(2-oxo-2H-chrome-3yl ethylidene] -hydrazinecarbodithionic acid benzyl ester (L2H) have been synthesized. All the synthesized compounds were characterized by elemental analyses, melting point determinations and a combination of electronic, IR...

Arsenic is classified as a carcinogen for humans, but as a possible genotoxic agent. Thus, taking into account the controversial data about how arsenic compounds are able to induce genetic damage, we investigated the possible genotoxic activity of different arsenic compounds in the TK6 human lymphoblastoid cell line using the alkaline Comet assay. Eight different inorganic and organic arsenical...

26 Arsenic (As) exists in a variety of chemical forms, and microbial metabolism results in 27 the occurrence of thermodynamically unstable arsenite (As) and methylarsenic compounds 28 in freshwaters (rivers and lakes). The inorganic forms (As and As) and the methylated 29 forms (methylarsonic acid; MMAA and dimethylarsinic acid; DMAA) are the main species 30 of As in freshwaters while the bulk ...

This work focuses on the analysis of genotoxic effects on human peripheral lymphocytes exposed in vitro to different arsenic (As) compounds by means of the cytokinesis-block micronucleus assay. The study was carried out by challenging peripheral human lymphocytes with six As compounds in trivalent or pentavalent forms such as arsenite (As(III)) and arsenate (As(V)) and organoarsenic species suc...