Hypersensitivity to TMJ implant materials is an issue that we are frequently hearing from TMJ patients. Given this concern we contacted Marco Caicedo, Ph.D., Senior Scientists and COO at Orthopedic Analysis in Chicago, IL. Orthopedic Analysis is an independent diagnostics company dedicated to the quantitative analysis of immune responses to biomaterials (i.e metal allergy to implant materials)....

During the past few decades, increased aging of world population has prompted search for novel and improved materials orthopedic implant applications [...]

We report here the genome sequence of a clinical isolate of Staphylococcus aureus from an orthopedic infection. Phenotypically diverse Staphylococcus aureus strains are associated with orthopedic infections and subsequent implant failure, and some are highly resistant to antibiotics. This genome sequence will support further analyses of strains causing orthopedic infections.

The development of better orthopedic implants is incessant. While current implants can function reliably in the human body for a long period of time, there are still a significant number of cases for which the implants can fail prematurely due to poor osseointegration of the implant with native bone. Increasingly, it is recognized that it is extremely important to facilitate the attachment of o...

Magnesium-Calcium (Mg-Ca) alloy has received considerable attention as an emerging biodegradable implant material in orthopedic fixation applications. The biodegradable Mg-Ca alloys avoid stress shielding and secondary surgery inherent with permanent metallic implant materials. They also provide sufficient mechanical strength in load carrying applications as opposed to biopolymers. However, the...

A partial review is proposed on the existing literature for the research performed in orthopedic implant used as drug delivery system. In the first part, an evaluation is given on the clinical need to deliver a drug in the surrounding of an implant. Secondly, a review of the clinical situation is developed for implants already used as drug delivery system. Experimental works performed for local...

Implant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. surface modifications coatings are being developed to promote osteointegration, prevent colonization by bacteria, release bioactive factors. The following mini-review briefly discusses the clinical problem, explains four “osteos”, presents examples of used for ...

Orthopedic implant infections have been steadily increasing while, at the same time, antibiotics developed to kill such bacteria have proven less and less effective with every passing day. It is clear that new approaches that do not rely on the use of antibiotics are needed to decrease medical device infections. Inspired by cicada wing surface topographical features, nanostructured surfaces rep...