Bone tissue reconstruction with extensive damage is one of the challenges for dentists because its healing process bone tissue. graft gold standard repair. However, use has a limited amount produced. Tissue engineering latest method in terms regeneration. three main components, first stem cells that have self renewal ability and multineage differentiation, second bioreactor / growth factor, the...

Bone morphogenetic protein (BMP) appears to be one of the most promising cytokine and for clinical use in reconstructive surgery for bony defects and augmentation. To evaluate the effect of basic fibroblast growth factor (bFGF), FK506, elcatonin, and hyperbaric oxygenation (HBO) on osteoinduction by recombinant human bone morphogenetic protein-2 (rhBMP-2), 2 or 5 μg of rhBMP-2 was implanted int...

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Reconstruction of extensive bone tissue damage is a treatment with complication. Because moving the autologous such as graft can cause complications that causes problems in repair so, principle engineering (stem cells, bioreactor / growth factor, and scaffold) used an alternative to reconstruct because it has many advantages. The combination hADMSC chitosan scaffold, expected trigger osteoinduc...

The progressive loss of endogenous regenerative capacity that accompanies mammalian aging has been attributed at least in part to alterations in the extracellular matrix (ECM) composition of adult tissues. Thus, creation of a more regenerative microenvironment, analogous to embryonic morphogenesis, may be achieved via pluripotent embryonic stem cell (ESC) differentiation and derivation of devit...

BACKGROUND Cell therapy using autologous cells has been used in the treatment of various medical conditions. The mononuclear cell (MNC) fraction of bone marrow (BM) contains stem/progenitor cells that could contribute to osteogenesis and angiogenesis. QUESTIONS/PURPOSES We asked whether MNCs derived from intraoperative shed blood (SB), consisting of peripheral blood and BM, have osteoinductiv...

This work studies osteoinduction and bone conduction in polyvinyl alcohol-tetraethylorthosilicate-alginate-calcium oxide (PTAC) biocomposite cryogels along with the synergistic effect of electrical stimulation. In vitro osteoinduction of C2C12 myoblast towards osteogenic lineage is demonstrated through alkaline phosphatase assay, scanning electron microscopy and energy dispersive X-ray spectros...