نتایج جستجو برای: ovarian development
تعداد نتایج: 1489267 فیلتر نتایج به سال:
background ovarian cancer is the most common fatal gynecologic malignancy in women. the brca2 gene has a role in regulation of cell cycle during proliferation, differentiation and dna repair. changes in the methylation of brca2 may be an effective mechanism for ovarian cancer. objectives the aim of the present study was to evaluate the association between ovarian cancer and methylation status o...
Pre-natal and early post-natal ovarian development has become a field of increasing importance over recent years. The full effects of perturbations of ovarian development on adult fertility, through environmental changes or genetic anomalies, are only now being truly appreciated. Mitigation of these perturbations requires an understanding of the processes involved in the development of the ovar...
Purpose: Several causes for primary ovarian insufficiency have been described, including iatrogenic and environmental factor, viral infections, chronic disease as well as genetic alterations. Given the large number of genes described in the literature so far, the aim of this review was to collect all the genetic mutations associated with non-syndromic primary ovarian insufficiency. Methods: All...
The aim of this study was to evaluate the effects of ovarian tissue vitrification and two-step in vitro culture on the metaphase II (MII) oocyte reactive oxygen species (ROS) level, mitochondrial transcription factor A (TFAM) expression and succinate dehydrogenase (SDH) activity. After collection of neonatal mouse ovaries, 45 ovaries were vitrified and the others (n = 45) were...
background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...
In the present investigation, vitellogenesis during ovarian development in the freshwater prawn Macrobrachium rosenbergii was assessed. Ovarian development was classified into five stages based on size, colour and texture of ovary. Interestingly, histological results clearly indicate that the oocyte development gradually increased from stages I to V based on the yolk material accumulation. Besi...
to study the effect of dietary animal and plant lipids on gonadal differents and sex steroid hormones levels of blood in rainbow trout (oncorhynchus mykiss), the four diets was formulated based on 15% fat. the control uses 100% oil, fish oil was treated in the first, second and third respectively 25% and 75% fish oil, soybean oil, canola and cotton were used. after six weeks of feeding fish wit...
Infertility is a main manifestation of endometriosis, though the exact pathogenesis endometriosis-associated infertility remains unclear. Compromised ovarian functions may be one causes endometriosis related infertility. The function can classified into three basic elements, (1) production hormones, (2) maintenance follicular development until ovulation, and (3) reservoir dormant oocytes (ovari...
BACKGROUND The genetic causes of nonsyndromic ovarian insufficiency are largely unknown. A nuclear receptor, NR5A1 (also called steroidogenic factor 1), is a key transcriptional regulator of genes involved in the hypothalamic-pituitary-steroidogenic axis. Mutation of NR5A1 causes 46,XY disorders of sex development, with or without adrenal failure, but growing experimental evidence from studies ...
Introduction: Ovarian cancer is caused by malignant changes in the cells of the ovary. In various studies, cancer has been regarded as a biological system that has a set of characteristics; therefore, presenting a model of this system can considerably help to study and predict the phenomena related to the growth and spread of cancer. This study attempted to model and simulate the growth and spr...
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