OBJECTIVES Using ovariectomized rats, we examined the influence of combined exercise tolerance and natto intake on the bone loss inhibitory effect. METHODS We divided female Wistar rats into the following groups: Ovariectomy, Ovariectomy + Exercise, Ovariectomy + Natto Intake, Ovariectomy + Exercise + Natto Intake, and Pseudo-operative (Sham group). After conducting experiments on each group,...

MTW9, a transplantable mammary tumor in Wistar Furth rats, shows little growth unless host serum prolactin is increased. This study compares the response to ovariectomy of MTW9-MtT, a tumor developed in rats bearing the mammosomatotropic tumor MtTW10 (serum prolactin 500 to 7000 ng/ml) with MTW9-P developed in rats given chronic perphenazine treatment (4 mg/kg/day). Serum prolactin concentratio...

The present study evaluated and compared the oxidative stress status of dogs undergoing laparoscopic or open ovariectomy. Twelve healthy female dogs were divided into two groups according to the type of the surgical procedure, laparoscopic or open ovariectomy. Plasma total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) levels for the evaluation of oxidativ...

BACKGROUND The plant Cissus quadrangularis (CQ) is used as an osteoprotective agent in Ayurveda, the Indian system of alternative medicine. The present study was done to validate the anti-osteoporotic role of the petroleum ether extract of CQ on ovariectomy-induced osteoporosis in rats. METHODS Female wistar rats were divided into five groups of six rats each; (1) The Normal control (NC) grou...

OBJECTIVE To describe laparoscopic ovariectomy and salpingectomy in the African lioness (Panthera leo). STUDY DESIGN Descriptive clinical study. ANIMALS Female lions (n = 16). METHODS Lionesses were randomly divided into 2 groups: O = ovariectomy (n = 8) and S = salpingectomy (n = 8) for laparoscopic surgery. Two Veress needle placement techniques were used. RESULTS Laparoscopic ovariec...

It has been reported that loss of ovarian oestrogen after menopause or by ovariectomy causes osteoporosis. In order to elucidate the effect of dietary protein restriction on bone metabolism after ovariectomy, we fed ovariectomized young female rats on a casein-based diet (50 g/kg diet (protein restriction) or 200 g/kg diet (control)) for 3 weeks and measured mRNA contents of bone-matrix protein...

The growth of mammary carcinoma induced by oral 3-methylcholanthrene in female Wistar rats is retarded by ovariectomy and by food restriction sufficient to produce 12-14% body weight loss. Estradici benzoate (NSC 9566), 5-fluorouracil (NSC 19893), miracil D (NSC 14574), mitomycin C (NSC 26980), and AB-100 (NSC 37095) showed inhibitory activity. The best tumor inhibition without mortality was el...

Ovarian hormones are associated with binge eating in women, however findings are limited by the lack of experimental control inherent in human studies. Animal research that manipulates ovarian hormone status and examines individual differences in extreme binge eating proneness is needed to model clinical phenotypes in humans and to confirm causal effects. The purpose of this study was to examin...

AIM To evaluate in a rat animal model whether ovariectomy, high fat diet (HFD), and physical activity in the form of running affect leptin receptor (Ob-R) distribution in the brain and white fat tissue compared to sham (Sh) surgery, standard diet (StD), and sedentary conditions. METHODS The study included 48 female laboratory Wistar rats (4 weeks old). Following eight weeks of feeding with st...

The growth of mammary carcinoma induced by oral 3-methylcholanthrene in female Wistar rats is retarded by ovariectomy and by food restriction sufficient to produce 12-14% body weight loss. Estradici benzoate (NSC 9566), 5-fluorouracil (NSC 19893), miracil D (NSC 14574), mitomycin C (NSC 26980), and AB-100 (NSC 37095) showed inhibitory activity. The best tumor inhibition without mortality was el...