Objective(s): The objective of the present study is to explore whether Nanocurcumin improves pancreatic inflammation through the inhibition of the TLR4/NFkB signaling pathway in cerulein-induced acute pancreatitis. Methods: Acute pancreatitis was induced by five intraperitoneal (i.p.) injection of cerulein (50 μg/kg) with 1h intervals. Vehicle and nanocurcumin (100mg/kg/day) were given to the a...

autoimmune pancreatitis is a fibro-inflammatory form of chronic pancreatitis. it is diagnosed by the combination of imaging studies such as a ct scan and pancreatography, laboratory analyses that include igg4 and/or autoantibodies, histopathological evaluations and positive response to corticosteroid therapy. we report the case of a 41-year-old female with a history of jaundice and increasing a...

post endoscopic retrograde cholangiopancreatography (ercp) pancreatitis is a frequent complication either for diagnosis or treatment of pancreatobiliary diseases. a number of pharmacological agents have been tried for prevention or alleviation of the complication. allopurinol with free radical scavenger property has been considered as an effective prophylactic agent in some clinical trials. adm...

background: acute pancreatitis is a common complication of endoscopic retrograde cholangiopancreatography (ercp). several medical and surgical procedures have been analyzed in prevention of post-ercp pancreatitis as a major post-ercp complication, so we conducted a study to assess the role of prophylactic pancreatic stents on prevention and severity of post-ercp pancreatitis. materials and meth...

objectives: acute pancreatitis is an inflammatory condition of pancreas with sudden onset, high mortality rate and multiple organ failure characteristics. it has been shown that oxygen free radicals have an important role in development of pancreatitis and its complications. antioxidant, anti-inflammatory, anti-hepatotoxicity and gastroprotective properties of cichorium intybus l. suggest that ...

Introduction: Chronic pancreatitis is defined as a persistent pancreatic inflammatory disease. In chronic pancreatitis, recurrent episodes of inflammation lead to the replacement of pancreatic parenchyma with fibrotic connective tissue. Chronic pancreatitis pain, which may initially mimic acute pancreatitis, is severe, frequent, and continual and has a major impact on the quality of life and so...

one of the most important and serious disorders of gastrointestinal tract is acute pancreatitis which in severe form is associated with high mortality rate particularly in the presence of systemic inflammatory response and multiple organ failure. apoptosis linked to oxidative stress has been shown in the pancreas of the patients with acute pancreatitis. lithium, one of the most effective drugs ...

 Abstract Fat necrosis secondary to pancreatitis can be either mild and self limited or create severe organ damage, but may rarely lead to abdominal opancreatic pseudotumor. We report a case of fat necrosis secondary to pancreatitis which clinically simulates transverse colon cancer.

abstract fat necrosis secondary to pancreatitis can be either mild and self limited or create severe organ damage, but may rarely lead to abdominal opancreatic pseudotumor. we report a case of fat necrosis secondary to pancreatitis which clinically simulates transverse colon cancer.