Recent advances in high-throughput methods and the application of computational tools for automatic classification of proteins have made it possible to carry out large-scale proteomic analyses. Biological analysis and interpretation of sets of proteins is a time-consuming undertaking carried out manually by experts. We have developed PANDORA (Protein ANnotation Diagram ORiented Analysis), a web...

The statistical machine translation (SMT) approach has taken a lead place in the field of Machine Translation for its better translation quality and lower cost in training compared to other approaches. However, due to the high demand of computing resources, an SMT system can not be directly run on hand-held devices. Most existing hand-held translation systems are either interlingua-based, which...

This paper contributes a new model for Design Research that extends existing approaches by taking into account the neglected areas of design seeking and scaling in the underexplored area of workplace informal learning; we place an emphasis on design that is based on a new empirically base. We use PANDORA as an exemplary case study to identify and illustrate the research benefits of the Design S...

This paper describes the design and development of an online immersive learning environment focused on supporting the general public in awareness of, and preparation for, crisis situations. The system developed uses the PANDORA + training environment, and integrates prior research work carried out on eLearning and Crisis Management. Specifically, it pulls together the outputs of three European ...

The development of automated solutions to pattern recognition problems is important in many areas of scientific research and human endeavour. This paper describes the implementation of the Pandora Software Development Kit, which aids the process of designing, implementing and running pattern recognition algorithms. The Pandora Application Programming Interfaces ensure simple specification of th...

Using classical combinatorial fault trees, analysts are able to assess the effects of combinations of failures on system behaviour but are unable to capture sequence dependent dynamic behaviour. Pandora introduces temporal gates and temporal laws to fault trees to allow sequence-dependent dynamic analysis of events. Pandora can be easily integrated in model-based design and analysis techniques;...

Multi-agency crisis management represents one of the most complex of real-world situations, requiring rapid negotiation and decision-making under extreme pressure. However, the training offered to strategic planners, called Gold Commanders, does not place them under any such pressure. It takes the form of paper-based, table-top exercises, or expensive, real-world, limited-scope simulations. The...

This short paper introduces a novel use of timeline-based planning as the core element of a dynamic training environment for crisis managers called PANDORA. A trainer is provided with a combination of planning and execution functions that allow him/her to maintain and adapt a “lesson plan” as the basis for the interaction between the trainer and a class of trainees. The training session is base...

T-box transcription factors are critical regulators of early embryonic development. We have characterized a novel zebrafish T-box transcription factor, hrT (H15-related T box) that is a close relative of Drosophila H15 and a recently identified human gene. We show that Drosophila H15 and zebrafish hrT are both expressed early during heart formation, in strong support of previous work postulatin...