OBJECTIVE: To evaluate the liquid-based ThinPrep Papanicolaou test. DESIGN: Prospective comparison of the ThinPrep test with the conventional Papanicolaou test. SETTING: Cervical smear specimens sent to a private practice, Hong Kong. PATIENTS: A total of 16,541 ThinPrep test specimens and 7258 conventional Papanicolaou smears from Hong Kong women who had been screened for cervical cancer betwee...

This paper traces the cervical Papanicolaou smear test from the seminal work of George Papanicolaou undertaken more than 70 years ago, to the present use of computer technology to examine cervical smears. However, to successfully detect cervical cancer and precursor lesions, the standard of the specimens, as well as that of the screening laboratory, must be of the highest order so that false ne...

BACKGROUND Cervical cancer is the second most common malignancy in women worldwide with a high incidence in under-developed countries and Nigeria is one of these countries. This study aimed at screening for cervical cancer using Papanicolaou smear and to identify risk factors for cervical cancer among women in Olufadi community, Kwara State, North-central Nigeria. METHODS This was a cross-sec...

OBJECTIVE To determine the ability of Multimodal Hyperspectral Imaging (MHI) to noninvasively detect, localize and diagnose cervical neoplasia. MATERIALS AND METHODS The cervical epithelium was interrogated by MHI using tissue fluorescence and reflectance measurements after the probe was placed on the ectocervix. A Papanicolaou smear was taken, and a colposcopic examination was performed and ...

OBJECTIVE We sought to evaluate the cytologic diagnosis and sample adequacy of the liquid-based cervical cytologic smear (ThinPrep) compared with that of the conventional Papanicolaou smear. STUDY DESIGN Prospective studies of ThinPrep and conventional Papanicolaou smears were analyzed for cytologic diagnosis and sample adequacy. Computerized databases, references in published studies, and in...

Over the past 50 years, the incidence and mortality of cervical cancer has decreased by 75 percent in developed countries because of the availability of screening program for cervical precancer and human papilloma virus (HPV) vaccination. In developing countries, however, cervical cancer remains the second most common type of cancer and cause of cancer death in women. This is most likely due to...

The Polarprobe is a portable non invasive electronic device designed for the detection of cervical precancer and cancer. It measures both electrical and optical properties of cervical tissue to allow a real time comparison with a databank of previously determined cervical tissue types. The need for additional tests to augment or even replace the Papanicolaou smear has partly prompted its develo...

OBJECTIVE To estimate whether women exposed in utero to diethylstilbestrol (DES) report receiving more cervical and general physical examinations compared to unexposed women. MATERIALS AND METHODS 1994 Diethylstilbestrol Adenosis cohort data are used to assess the degree of recommended compliance of cervical screenings found in 3,140 DES-exposed and 826 unexposed women. Participants were enro...

Cervical cancer is the third most common cancer worldwide, and over 88% of cases occur in developing countries (IARC, 2008). Cervical cancer, which is preventable and treatable, is the number one cancer killer of women in developing countries. Since the introduction of Papanicolaou (Pap) smear screening, cervical cancer prevention efforts worldwide have focused on screening women at risk of the...