INTRODUCTION The relationship between peripheral 5-HT3A receptor mRNA level and risperidone efficiency in paranoid schizophrenia patients is still unknown. METHODS A total 52 first-episode and drug-naive paranoid schizophrenia patients who were treated with risperidone and 53 matched healthy controls were enrolled. Patients were naturalistically followed up for 8 weeks. Positive and Negative ...

background: schizophrenia is a psychiatric disorder that impairs several intellectual functions, including attention processes.   objectives: to investigate attention deficit in a group of patients with schizophrenia.   method: thirty patients with schizophrenia hospitalized in three psychiatric wards in shiraz and isfahan and 30 normal healthy subjects matched for age, gender and years of educ...

The Span of Apprehension task represents a putative cognitive vulnerability marker for schizophrenia. To investigate the nature of the scanning deficits on the Span of Apprehension shown by patients with paranoid schizophrenia a wide visual angle partial report version of the task was administered to 18 paranoid schizophrenics and 18 normal controls. An analysis of scan paths, based upon target...

INTRODUCTION Neuropsychological aspects of paranoid schizophrenia have still not been examined enough.These disorders are usually not studied separately, but are included in the studies about schizophrenic patients with positive symptoms. Despite the fact that schizophrenia represents a heterogeneous group of mental disorders, usually it is not separated from schizoaffective disorder in neurops...

In a Study Of 90 patients of Alcoholic Hallucinosis and 30 patients of Paranoid Schizophrenia, it was found that delusions, delusions of infidelity, third person and running commentary auditory hallucinations and insight were not different in the two groups.Delusions of grandeur, passivity, thought echo and thought broadcast were significantly more frequent in paranoid schizophrenic patients. A...

This study examined agreement between clinical diagnoses and research diagnoses of schizophrenia for a sample of African American patients recently admitted to a psychiatric hospital. It also examined the association of cultural mistrust with disagreement between clinical diagnoses and research diagnoses of the paranoid subtype of schizophrenia. Complete data was available for 118 (77%) of the ...

A converging body of clinical and empirical reports indicates that autism features elevated rates of paranoia comparable to those of individuals with paranoid schizophrenia. However, the distinct developmental courses and symptom manifestations of these two disorders suggest that the nature of paranoid ideation may differ between them in important and meaningful ways. To evaluate this hypothesi...

Whether avoidant personality disorder symptoms are related to neurocognitive impairments that aggregate in relatives of schizophrenics is unknown. We report the relationship between avoidant personality disorder symptoms and neurocognitive performance in the first-degree relatives of probands with schizophrenia. 367 first-degree relatives of probands with schizophrenia and 245 relatives of comm...

Delusional paranoia has been associated with severe mental illness for over a century. Kraepelin introduced a disorder called "paranoid depression," but "paranoid" became linked to schizophrenia, not to mood disorders. Paranoid remains the most common subtype of schizophrenia, but some of these cases, as Kraepelin initially implied, may be unrecognized psychotic mood disorders, so the relations...

Background: Schizophrenia is a psychiatric disorder that impairs several intellectual functions, including attention processes.  Objectives: To investigate attention deficit in a group of patients with schizophrenia.  Method: Thirty patients with schizophrenia hospitalized in three psychiatric wards in Shiraz and Isfahan and 30 normal healthy subjects matched for age, gender and years of educat...