Pseudohypoparathyroidism is a rare disorder which is characterized by end organ parathormone resistance, which causes hypocalcaemia, hyperphosphataemia and high parathormone levels. We are reporting here case of a young male who had symptoms of chronic hypocalcaemia, with a positive Trousseau's and Chvostek's sign on examination, without any features of Albright's hereditary osteodystrophy. Lab...

background vitamin d (vit d) level may change variously in serums of patients undergoing anti-tuberculosis (anti-tb) therapy using antibiotics such as isoniazid and rifampin. objectives the current study aimed to evaluate all components of calcium (ca) regulatory agents in the six- month period of standard anti- tb therapy. patients and methods eight adults whose pulmonary tb had been diagnosed...

It has been demonstrated recently that human growth hormone (HGH) increases the tubular reabsorption of phosphate in man (1, 2). This effect is probably responsible for the fall in urinary excretion of phosphate and the rise in plasma level of phosphorus produced by growth hormone (GH) and may also explain the elevation of plasma phosphorus found in acromegaly. The action of GH on tubular trans...

AIM To determine the incidence of hypocalcaemia in critically ill children with meningococcal disease. METHODS In a prospective cohort study, 70 of 80 patients admitted consecutively with a clinical diagnosis of meningococcal disease to intensive care had measurements of total and ionised calcium on admission. Parathormone and calcitonin were measured in a proportion of the children. RESULT...

INTRODUCTION It has been postulated that low vitamin D levels are associated with coronary artery diseases. Coronary artery ectasia (CAE) is associated with atherosclerosis, congenital cardiac defects, immunological diseases and connective tissue diseases. In this study, we aimed to investigate whether there is an association between vitamin D and parathormone levels and isolated coronary arter...

BACKGROUND The long-term significance of normocalcemic parathormone elevation (NPE) after successful parathyroidectomy for sporadic primary hyperparathyroidism remains unclear. METHOD Of 239 consecutive patients who underwent targeted parathyroidectomy with intraoperative parathormone monitoring, 96 were followed for ≥ 10 years. NPE was defined as a normal serum calcium level and parathormone...

INTRODUCTION Urolithiasis is a multifactorial disease. Changes in social and economic living conditions have generated changes in chemical composition of urolith too. Although calcium is a predominant crystalline constituent of kidney stones in 80% of cases, metabolic disorders are not the main reason for their formation. Hyperparathyroidism may be a cause of occurrence of calcium lithiasis, ho...