BACKGROUND AND OBJECTIVES The effects of calcitriol and paricalcitol on circulating levels of intact parathyroid hormone, parathyroid hormone-(1-84), the large carboxy-terminal-parathyroid hormone fragments, and the parathyroid hormone-(1-84)/carboxy-terminal-parathyroid hormone fragments were studied. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS In the longitudinal study, 31 hemodialysis pa...

This review examines the dynamics of parathyroid hormone secretion in health and in various causes of secondary hyperparathyroidism. Although most studies of parathyroid hormone and calcium have focused on the modification of parathyroid hormone secretion by serum calcium, the relationship between parathyroid hormone and serum calcium is bifunctional because parathyroid hormone also modifies se...

The present study determined the effects of 1,25-dihydroxycholecalciferol on serum immunoactive parathyroid hormone and on parathyroid hormone secretion in vitro. Rats injected i.p. with 1,25-dihydroxycholecalciferol, 130 pmol (2 U)/140 g body wt, which is probably a physiologic dose, had a significant 43% decrease in serum immunoreactive parathyroid hormone at 4 h. In addition, this dose of 1,...

BACKGROUND We evaluated whether patients with osteoporosis treated with long-term alendronate have a response to parathyroid hormone treatment and whether short, three-month cycles of parathyroid hormone therapy could be as effective as daily administration. METHODS We randomly assigned 126 women with osteoporosis who had been taking alendronate for at least 1 year to continued alendronate pl...

Parathyroid hormonelike protein from human renal carcinoma cells. Structural and functional homology with parathyroid hormone. Identification of a novel 17,000-Dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercal-cemia of malignancy. Synthetic human parathyroid hormone-like protein stimulates bone resorp-tion and causes hypercalcemi...

Severe and moderate osteoporosis is a common disease in the world. It considered silent that has no clear signs. The current study aimed to evaluate correlation between Parathyroid Hormone-related Protein (PTHrP) with Vitamin D Bind protein(VDBP) Osteoporosis Osteopenia patients AL-Najaf city /Iraq. To succeed desired goal, 100 (50 50 Osteoporosis) participated this study, on other hand, fifty ...

objectives: the purpose of this study was to consider the effect of eight weeks aerobic training on pth, albumin, calcium, alkaline phosphatesand estrogen levels in postmenopausal women. methods & materials: 22 postmenopause women, 55-70 years, of jahandidegan center in tehran were selected and randomly divided into two groups: (experimental (12) and control (10)) .they had aerobic training pro...

conclusions literature search revealed an increased prevalence of hypothyroidism with secondary hpth from renal failure. although there is increased prevalence of hypothyroid state in secondary hpth from renal failure, the association appears much weaker in primary hpth and again no conclusive pathological relation has been identified between the two endocrine glands. a closer look and perhaps ...

Acute parathyroid hormone exposure induces vascular smooth muscle relaxation. In contrast, continuous infusion of parathyroid hormone leads to vasoconstriction and an elevation of blood pressure. Despite the known effects of parathyroid hormone on vascular smooth muscle, possible direct effects on the vascular endothelium have not previously been investigated. Using a human umbilical vein endot...

Background: Nowadays, cardiovascular diseases (CVDs) are among the most common causes of mortalities worldwide. Parathyroid hormone (PTH) has an important role in the pathogenesis of CVDs. The aim of the current study was to compare serum PTH levels between patients with acute myocardial infarction (MI), unstable angina, and normal coronary function. Methods: This descriptive and analytic stud...