The distribution behavior of ofloxacin enantiomers was examined in the aqueous and organic solvent of a two-phase system containing chiral selector L-tartarate. The effect of extraction equilibrium time, buffer pH, organic solvents and length of alkyl chain of L-tartarate on the partition coefficients and enantioselectivity of racemic ofloxacin were investigated, respectively. The L-tartara...

For a graph $G = (V, E)$, a partition $pi = {V_1,$ $V_2,$ $ldots,$ $V_k}$ of the vertex set $V$ is an textit{upper domatic partition} if $V_i$ dominates $V_j$ or $V_j$ dominates $V_i$ or both for every $V_i, V_j in pi$, whenever $i neq j$. The textit{upper domatic number} $D(G)$ is the maximum order of an upper domatic partition. We study the properties of upper domatic number and propose an up...

In the present study, natural convective heat transfer in a partitioned square cavity utilizing nanofluids is studied. The vertical left and right walls are considered as the hot and cold walls, respectively and the partitions assumed to be adiabatic. The nanofluid used in this study is Al2O3 with the volume fraction of 20%. It is assumed that nanofluid is a single phase f...

Partition curves are widely used to determine the spiral separator efficiency. In this work, the partition curves were used in order to investigate the particle transportation to concentrate and tailing streams. Simulation of fine particle removal using the size-by-size partition curves showed that the recovery of gangue particles to concentrate can decrease 8.7%. It also showed that the recove...

transfusion-dependent patients such as those suffering from β-thalassaemia develop a fatal secondary haemosiderosis and consequently a selective iron chelator must be used to relieve such iron overload. 3- hydroxypyridin-4-ones are selective for iron(iii) under most biological conditions, but unlike desferrioxamine, are efficiently absorbed when administered orally. in this study, the synthesis...

iron overload is a serious clinical condition which can be largely prevented by the use of iron-specific chelating agents. in this study, the synthesis and determination of partition coefficients (kpart) of a range of n-alkyl hydroxypyridinones, as orally active iron chelators, are described. synthesis of n-aryl hydroxypyridinones was achieved via a single step synthetic pathway. in this method...

Cephalexin is an important antibiotic. It is very significant to determine an appropriate method for the extraction of this valuable antibiotic for industrial applications. Aiming at developing an efficient method for the extraction of cephalexin, the partitioning of cephalexin has been evaluated in aqueous two-phase system, including cholinium chloride and potassium phosphate. The effect of th...

the partition coefficients (p-values) of certain new potential, stereoselective, reversible, long-acting local anesthetics have been determined in an n-octanol/ phosphate buffer system. these are derivatives of 2-phenoxyethyldialkylamine hydrochloride, and almost all of them are readily soluble in water. their aqueous solutions have shown different absorption maxima, and these have been used qu...