Fertilized chicken eggs were injected with high doses of individual polychlorinated biphenyl (PCB) congeners (0.5 microg of PCB 77, 9.8 microg of PCB 153, or 10.9 microg of PCB 180) before incubation to investigate the structure-specific uptake of these compounds by the embryo and their accumulation in brain and liver tissue. In accordance with earlier publications, a gradual uptake and accumul...

As part of an environmental health study of northwest Florida, we conducted an initial screening level assessment of contaminants in blue crabs (Callinectes sapidus) and oysters (Crassostrea virginica) collected in bays and bayous in the Pensacola, FL area. Tissue samples were analyzed for mercury, arsenic, cadmium, chromium, copper, lead, nickel, selenium, tin, zinc, 17 dioxin/furan compounds,...

A gas-chromatographic method on capillary columns is described for measuring concentrations of total PCBs and of six PCB congeners, PCB-28, PCB-52, PCB-101, PCB-138, PCB-153 and PCB-180, in human blood serum. Recovery of compounds was evaluated, and the repeatability and reproducibility of the results tested on samples analysed on the same day and over a period of two years. The method was veri...

Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants that can induce neurological defects in infants and children via placental and lactational transfer. To investigate the lactational transfer of PCBs and compare pharmacokinetic interactions among nonpregnant, lactating mice and suckling pups, quantitative time-course measurements of PCB accumulation in tissues were perfo...

Objective: The objective of this research is to examine PCB compounds in the Persian Gulf in the Southern Pars area. Methods: In the research, 6 stations were sampled: Asalouyeh Port, Kangan Site, Mehr Petro Kima Petrochemical, 4th Refinery in Southern Pasr, Taheri Port and Aria Sasol Polymer. To sample water in the stations determined, one-liter sampling bottles of dark glass were used. In eac...

The objective of this study was to examine the importance of nutrient status of a diatom (Stephanodiscus minutulus) to the uptake of PCB congener #54 (2,2',6,6'-tetrachlorobiphenyl) and the subsequent transfer of PCB to a pelagic grazing zooplankton (Daphnia pulicaria). The algae, which were grown under different nutrient treatments, were then fed to a zooplankton to examine the subsequent food...

We studied the effect of polychlorinated biphenyls (PCBs) on hepatic porphyrin accumulation in female Sprague-Dawley rats by feeding them diets containing 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153), 2,3,3',4,4',5-hexachlorobiphenyl (PCB 156), 3,3',4,4',5-pentachlorobiphenyl (PCB 126), or combinations of the single PCB congeners with TCDD for 13 weeks...

Muscle samples were collected from pup, juvenile and adult Weddell seals (Leptonychotes weddellii) near McMurdo Sound, Antarctica during the austral summer of 2006. Blubber samples were collected from juvenile and adult seals. Samples were analyzed for emerging and legacy persistent organic pollutants (POPs) including current and historic-use organochlorine pesticides, polychlorinated biphenyls...

Epidemiological and laboratory studies link polychlorinated biphenyls and their metabolites to adverse neurodevelopmental outcomes. Several neurotoxic PCB congeners are chiral and undergo enantiomeric enrichment in mammalian species, which may modulate PCB developmental neurotoxicity. This study measures levels and enantiomeric enrichment of PCB 95 and its hydroxylated metabolites (OH-PCBs) in ...

A follow-up study of capacitor manufacturing workers exposed to polychlorinated biphenyls (PCBs) and their children was conducted since 1973. PCB levels in whole blood of workers as well as in breast milk of the exposed lactating mothers were approximately 10 to 100 times those of nonexposed Japanese. Blood PCB levels had a statistically significant correlation with the duration of PCB handling...