Paracoccidioidomycosis (PCM) is a systemic mycosis, endemic in most Latin American countries, especially in Brazil. It is caused by the thermo-dimorphic fungus of the genus Paracoccidioides (Paracoccidioides brasiliensis and Paracoccidioides lutzii). Innate immune response plays a crucial role in host defense against fungal infections, and neutrophils (PMNs) are able to combat microorganisms wi...

Model-based Quality of Service (QoS) prediction approaches enable an early identification of bottlenecks in the design of complex software systems. In addition, they allow software architects to evaluate design decisions against each other. In data-intensive business applications, database accesses have a significant impact on a system’s QoS. Therefore, these accesses need to be considered in o...

A review of 400 clinical records of paracoccidioidomycosis (PCM) patients, 93 with the acute/subacute (AF) and 307 with the chronic form (CF), attended from 1977 to 2011, selected as to the schedule of release for study by the Office of Medical Records at the University Hospital of the Faculdade de Medicina de Botucatu-São Paulo State University--UNESP, was performed to detect cases in relapse....

Phase change memory (PCM) has emerged as a promising candidate for next-generation memories, owing to its low power consumption, non-volatility, and high storage-density. However, PCM has limited write endurance, i.e., it can only undergo a limited number of write operations, leading to a short lifecycle. Thus, it is an important issue to find out an efficient way to use PCM in memory hierarchy...

Although it is known that the centrioles play instructive roles in pericentriolar material (PCM) assembly and that the PCM is essential for proper centriole formation, the mechanism that governs centriole-PCM interaction is poorly understood. Here, we show that ATF5 forms a characteristic 9-fold symmetrical ring structure in the inner layer of the PCM outfitting the proximal end of the mother c...

Plasma cell mastitis (PCM), a particular type of mastitis, mainly occurs in females at nonpregnant and nonlactating stages. The infiltration of abundant plasma cells and lymphocytes is the hallmark of the disease. The incidence rate of PCM increased gradually and its pathogenesis remained unclear. In this study, we investigated the expression of IL-6/STAT3 signaling pathway, which is vital not ...

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both proteins then assemble into co-dependent scaffold-like structures that spread outwards from the m...

Organic phase change material (PCM) with macro-encapsulation is attractive in energy storage applications as it has relatively low cost. This study focuses on using PET plastic pipes to encapsulate paraffin and using low-cost float stones to increase the thermal conductivity of PCM modules as they have a special structure of high porosity. Float stones were immersed in the liquid PCM and an ult...

This study develops a novel composite phase change material (PCM) based onparaffin/hydrophobic expanded perlite and exfoliated graphene nanoplatelets as heat transferpromoter. The experimental analysis was systematically carried out on fabrication,characterization and testing the thermal storage properties of composite PCM. The micro-morphology characteristics of composite PCM s...

We give an overview on a novel framework for content–based multimedia retrieval. In this paper we present an implementation for audio identification. This framework consists of an index–based search combining algebraic methods with classical full–text retrieval. In the main part of the paper we propose several feature extractors which may be used for indexing the PCM audio data. We give an over...