During childhood and adolescence, bone mass acquisition occurs primarily through skeletal growth. It is widely assumed that bone mass acquisition throughout childhood is an important determinant of the risk of osteoporosis in late adulthood; bone mass is thought to resemble a bank account in which deposits persist indefinitely. However, several well-controlled clinical studies suggest that incr...

BACKGROUND The incidence of fragility fractures has increased during the last half of the 1990's. One important determinant of fractures is the bone mineral content (BMC) or bone mineral density (BMD), the amount of mineralised bone. If we could increase peak bone mass (the highest value of BMC reached during life) and/or decrease the age-related bone loss, we could possibly improve the skeleta...

osteoporosis (op) is a frequent complication of rheumatoid arthritis (ra) and longitudinal studies have documented increased rate of bone loss in ra patients. to determine the frequency of low bone mass as well as the influence of disease duration and corticosteroid use on bone mass in patients with ra, 88 patients with ra and 112 age matched controls were studied. bone densitometry was perform...

Osteoporosis is the most common metabolic bone disorder. It is defined as “a skeletal disease, characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture” [1]. Bone is a highly metabolic tissue, incorporating multiple functions such as stabilization of the body, protection of the inner organs an...