BACKGROUND Invasive fungal infection (IFIs) is a major infectious complication in immunocompromised patients. Early diagnosis and initiation of antifungal therapy is important to achieve the best outcome. OBJECTIVES The current study aimed to investigate the incidence of IFIs and evaluate the diagnostic performance of non-invasive laboratory tests: serologic (β-D-glucan, galactomannan) and mo...

Background & Aims: Fungal infections are among the most common life threatening conditions in patients with hematologic malignancies. The present study was carried out on children hospitalized in Amir Oncology Hospital of Shiraz, Iran, in order to determine the prevalence of fungal infections and respective susceptibility patterns to prophylactic antifungal therapies. Methods: Colonization was ...

a unique case of xanthoma in the external ear canal pediatric patient is presented this report. We describe and resume current literature on xanthomas head neck area. clinical intraoperative findings are reported presumed mechanisms for emergence discussed. furthermore described pathologic immunohistochemical characteristics. mostly seen patients with lipid metabolism disorders or hyperlipidemi...

introduction: autologous stem cells have greatly influenced the treatment of a variety of malignancies including hodgkin/non-hodgkins lymphoma and acute leukemias. this is a preliminary study comparing the time of engraftment, mortality rate and cost of treatment in outpatient versus inpatient autologous stem cell transplantation (sct) in iran. patients and methods: 11 outpatients (6 hodgkin ly...

Diffuse alveolar hemorrhage (DAH) is a life-threatening pulmonary complication in patients with hematologic malignancies or autoimmune disorders. The current treatment options, which include corticosteroids, transfusions, extracorporeal membrane oxygenation (ECMO), and immunosuppressants, have been limited and largely unsuccessful. Recombinant activated factor VII (rFVIIa) has been successfully...

BACKGROUND Human T-lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified in human. The current evidence is quite scarce regarding the potential role of HTLV-1 in pathogenesis of hematologic disorders and non-hematologic malignancies. OBJECTIVES The aim of this study is to evaluate the prevalence of HTLV-1 infection in patients with hematologic disorders and non-hematologic ma...