nephrotic syndrome is the commonest glomerular disease. typical symptoms could be proteinuria, low serum albumin and oedema. the mechanism of proteinuria in nephrotic syndrome is a defective glomerular filtration barrier. renal biopsy is the gold standard for diagnosis of nephrotic syndrome currently which is invasive and based on histopathological features, therefore it seems to be necessary to...

background and aim: steroid-resistant nephrotic syndrome (srns) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. these patients are at risk of developing end-stage renal disease. the aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with srns.materials and met...

PURPOSE To evaluate the efficacy of needle biopsy for diagnosing Wilms tumor (WT) before chemotherapy. MATERIALS AND METHODS We reviewed our institutional experience with Tru-Cut biopsy of pediatric renal masses in patients who subsequently underwent nephrectomy. We compared biopsy pathology with nephrectomy specimens to determine if biopsy accurately predicted final pathology. RESULTS Seve...

OBJECTIVE We present our experience in a series of 17 consecutive pediatric patients submitted to retroperitoneal laparoscopic renal biopsy. MATERIALS AND METHODS Retroperitoneal laparoscopic renal biopsy (LRB) was performed in 5 boys and 12 girls. Mean age was 8.1 years and age range from 2 to 12. Two or three trocars were used to expose the inferior pole of the kidney, remove enough cortica...

Background Chronic kidney disease is a global health concern, its detection and diagnosis in earlier stages is also a great challenge that can alleviate this burden. Kidney biopsy is important to establish histopathological patterns. But, it is invasive. We aimedto evaluate the correlation of renal resistive index (RI) measured by Doppler ultrasound with the prog...

OBJECTIVES To review pediatric cases of IgA nephropathy (IgAN) in 6 patients who underwent tonsillectomy and had marked improvement of their renal symptoms and to review the appropriate indications for tonsillectomy for this disease. DESIGN Retrospective case series. SETTING Academic medical center. PATIENTS Six children (age range, 8-15 years) with renal biopsy-proved IgAN who were refer...

Background: Regarding the significance of abdominal masses in children, we aimed to identify the pathology of masses according to the age and sex groups. Materials and Methods: We retrospectively reviewed pathological reports of 461 patients with abdominal mass that underwent resection or biopsy during the study period (25 years). Results: One hundred and eighty six cases (40%) were non-neo...

background this retrospective study aimed to determine the epidemiologic characteristics and risk factors of chronic kidney diseases (ckd) in patients < 18 years old at a single referral center. materials and methods in a hospital-based case control study, 66 ckd patients less than 18 years old were compared to 81 control patients (also under 18) without ckd. a patient was defined as a ckd case...

statement of problem: the effectiveness of fluoride dentifrices in reducing dental caries is well documented. however, not all fluoride dentifrices are equally effective purpose: the objective of this experimental study was to compare fluoride uptake from pooneh pediatric toothpaste and an ada-approved pediatric dentifrice, in sound enamel of primary teeth. materials and methods: in an in vitro...

Tubuloreticular inclusions (TRIs) are subcellular structures located within the cisternae of endoplasmic reticulum. Formation of TRIs has been linked to the exposure of excess interferon (IFN), either from endogenous or exogenous sources. In renal disease, TRIs have been most commonly associated with systemic lupus erythematosus (SLE), and human immunodeficiency virus-associated nephropathy (HI...