background : labeling, gathering mutual information, clustering and classification of central nervous system tumors may assist in predicting not only distinct diagnoses based on tumor-specific features but also prognosis. this study evaluates the epidemi- ological features of central nervous system tumors in children who referred to mahak’s pediatric cancer treatment and research center in tehr...

Spinal cord tumors in pediatric patients are rare, representing less than 1% of all central nervous system tumors. Two cases of pediatric primary intramedullary spinal cord glioblastoma at ages 14 and 8 years are reported. Both patients presented with rapid onset paraparesis and quadraparesis. Magnetic resonance imaging in both showed heterogeneously enhancing solitary mass lesions localized to...

Introduction: Spinal tumors are rare in the pediatric population, presenting many specific peculiarities when compared to adults. We have performed a broad narrative review to describe the most common spinal tumors in children, discussing their main characteristics and management options. Method: The authors have performed an extensive review of the peer-reviewed literature addressing the afo...

purpose: to report a case of spinal cord tumor with visual symptoms and papilledema due to increased intracranial pressure. patient and findings: a 24-year-old woman was referred because of recent blurred vision in both eyes. visual acuity was 20/25 and 20/20 in the right and left eyes, respectively. fundoscopy revealed bilateral papilledema. other ophthalmic examinations were normal. visual fi...

Pain is a frequent presenting symptom of spinal cord tumors in children and usually manifests as local spinal pain in the bony segments overlying the tumor. Two pediatric patients are presented in whom the diagnosis of intramedullary spinal cord tumors was delayed for many months because their pain was atypical. One had recurrent abdominal pain diagnosed as irritable bowel syndrome. The other h...

Pediatric spinal ependymomas (SEPN) are important albeit uncommon malignant central nervous system tumors with limited treatment options. Our current knowledge about the underlying biology of these tumors is limited due to their rarity. To begin to elucidate molecular mechanisms that give rise to pediatric SEPN, we compared the transcriptomic landscape of SEPNs to that of intracranial ependymom...

Tumors of the central nervous system are common in the pediatric population and constitute the second most prevalent tumor type in children. Within this group, spinal cord tumors are relatively rare and account for 1 to 10% of all pediatric central nervous system tumors. We describe a very rare case of an intradural extramedullary spinal cord tumor with a subcutaneous mass and discuss its clini...

BACKGROUND Despite previous research, prognostic factors for ependymoma remain relatively controversial. The purpose of our study was to examine demographic, clinical, and tumor attributes as potential predictors of survival using Surveillance, Epidemiology, and End Results (SEER) program data (1973-2007). METHODS All ependymoma (ICD-O-3 code 9391) and anaplastic ependymoma cases (ICD-O-3 cod...

Purpose: Pediatric spinal cord tumors are rare accounting for 4-6% of all primary CNS tumors in this age group. Collecting large number of cases has always been difficult due to their scarcity. SEER database provides a source on various tumors. Methods: We performed analysis on tumors of the spinal cord in patients between births to 20 years of age using the SEER data available for the period 1...

background metastatic spinal tumors are common and major causes of pathological spinal fractures that result in severe pain, weakness, and progressive neurological deficits. this study aims to evaluate the efficacy of percutaneous vertebroplasty (pvp) in pain-relief in patients with spinal fractures due to metastatic spinal tumors. methods we evaluated 25 documented cases of metastatic spinal t...