OBJECTIVE To determine the frequency of peptic ulcer disease in patients on nonsteroidal anti-inflammatory drugs (NSAID). METHODS Record of eight hundred and twenty consecutive patients undergoing upper gastrointestinal (GI) endoscopy; from January 1998 to December 2000 were reviewed. The endoscopic diagnosis varied from gastritis, peptic ulcer to duodenitis. The use of NSAID was documented b...

helicobacter pylori (h.pylori) is an etiologic factor for chronic gastritis and peptic ulcers. serological testing of h.pylori infection is common in iran, as other parts of the world. there are geographical variations in the humoral immune response to various h. pylori strains in different parts of the worl. we studied the immunogenic proteins of h.pylori by means of an immunoblot assay with a...

An idiopathic peptic ulcer is defined as an ulcer with unknown cause or an ulcer that appears to arise spontaneously. The first step in treatment is to exclude common possible causes, including Helicobacter pylori infection, infection with other pathogens, ulcerogenic drugs, and uncommon diseases with upper gastrointestinal manifestations. When all known causes are excluded, a diagnosis of idio...

AIM This study was carried out to assess the prevalence of Helicobacter pylori infection in various ABO blood groups of people of Kashmir. METHOD The study comprised 80 individuals - 50 peptic ulcer patients (whose disease was diagnosed by endoscopy) and 30 asymptomatic volunteers. Every subject's blood group and Rhesus status was determined by standard serological tests. Helicobacter pylori ...

Peptic ulcer embraces both gastric and duodenal ulcers and has been a major threat to the world’s population over the past two centuries, with a high morbidity and substantial mortality. Discovery of gastric mucosa infection with Helicobacter pylori (H. pylori) and its association with chronic antral gastritis and peptic ulcer revolutionized the treatment of ulcer illness. H. pylori are causall...

BACKGROUND/AIMS We investigated the prevalence and relationship of peptic ulcer disease and Helicobacter pylori infection to liver cirrhosis. METHODS We examined 288 patients with liver cirrhosis, 322 patients with non-ulcer dyspepsia, and 339 patients with peptic ulcer disease. Rapid urease test and Wright-Giemsa staining were used for diagnosis of H. pylori infection. RESULTS The prevalen...

AIM To study the association of Helicobacter pylori infection with chronic antral gastritis in peptic ulcer disease patients and healthy population of Kashmir. METHODS 50 peptic ulcer patients (duodenal ulcer = 46, gastric ulcer = 2 and combined duodenal and gastric ulcer = 2) and 30 asymptomatic healthy volunteers were included in this study. Peptic ulcer was diagnosed on endoscopic examinat...

Liver penetration is a rare but serious complication of peptic ulcer disease. We report a 60-year-old man, without any serious risk factor for peptic ulcer, presented with mild abdominal discomfort, food-related vomiting and weight loss, and a mass in the left hepatic lobe, which was the result of a silent duodenal ulcer penetration. The diagnosis was based on histological examination of the en...

1.1 Background Peptic ulcer disease (PUD) had a tremendous effect on morbidity and mortality until the last decades of the 20th century. Development of new effective and potent acid suppressants and the discovery of Helicobacter pylori (H. pylori) are two important steps that caused a reduction in the prevalence of peptic ulcer. With the discovery of H. pylori, causes, pathogenesis and treatmen...