Implant periapical lesions are infectious-inflammatory alterations surrounding an implant apex, and can be caused by a number of situations--including contamination at instrumentation, overheating of bone, and the prior existence of bone pathology. The diagnosis is based on the clinical manifestations and radiological findings, where a radiotransparency can be seen at periapical level. The lesi...

introduction: studies have shown the regulatory role of leptin in bone formation, its expression in adipose tissue as well as increased levels in circulation following the adminstration of inflammatory stimuli such as lipopolysaccharides (lps). however, there is little data evaluating the role of leptin in inflammatory periapical lesions. the aim of this study was to evaluate the presence and c...

Twenty-five human dental periapical lesions were obtained. The lesions were frozen, sectioned, and examined for the presence of immune complexes by employing an anticomplement immunofluorescence (ACIF) technique. Twenty-three of the periapical specimens were positive for antigen-antibody complexes. No staining was noted in the two lesions that were histologically diagnosed as periapical scar ti...

AIM To report a case of conservative nonsurgical management of periapical lesions. BACKGROUND Small periapical lesions of endodontic origin usually heal by conventional endodontic therapy alone. Larger periapical lesions presumed to be cystic may require additional treatment protocols to aid in regression. Conservative nonsurgical management of such lesions eliminates the possible complicatio...

introduction: an important consideration in endodontic treatment is the elimination of microorganisms, including fungi, from the complex three- dimensional root canal system. candida albicans (ca) has a major role in endodontic treatment failure as the most important fungus isolated from the root canal system. the present study was carried out to evaluate the presence of ca in the teeth requiri...

BACKGROUND/AIM Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive lesions. The aim of this study was to determinate the correlation between concentration of collagenases (MMP-1, -8, -13) in chronic periapical le...

OBJECTIVES Recent studies have investigated the occurrence of human cytomegalovirus and Epstein-Barr Virus in samples from apical periodontitis lesions and a role in the pathogenesis of this disease has been suggested. Because genotype distribution and seroprevalence of EBV and HCMV differ among populations, it is important to determine the presence of these viruses in endodontic periapical les...

Context: The essential role of a general dental practitioner is recognizing the nature of the oral cavity lesions. Periapical lesions, which are observed in radiographs of patients, may have odontogenic or nonodontogenic origins. This review aimed to study differential diagnosis of common and important periapical lesions. Evidence Acquisition: English-language literature were searched by manual...