نتایج جستجو برای: pert
تعداد نتایج: 705 فیلتر نتایج به سال:
AIM Because of increasing awareness of variations in the use of pancreatic exocrine replacement therapy, the Australasian Pancreatic Club decided it was timely to re-review the literature and create new Australasian guidelines for the management of pancreatic exocrine insufficiency (PEI). METHODS A working party of expert clinicians was convened and initially determined that by dividing the t...
Adapting a Delay-based Protocol to Heterogeneous Environments. (August 2008) Kiran Kotla, B.E., Birla Institute of Technology and Science, Pilani, India Co–Chairs of Advisory Committee: Dr A. L. Narasimha Reddy Dr Riccardo Bettati We investigate the issues in making a delay-based protocol adaptive to heterogeneous environments. We assess and address the problems a delay-based protocol faces whe...
Phenol emulsion reassociation technique (PERT) greatly enhances the rate of DNA hybridization in solution over typical hybridization conditions (1) and has successfully been used to accelerate competitive DNA reassociation for performing subtraction based genomic cloning (2-5). PERT is accomplished through the establishment and maintenance of a phenol emulsion, typically by mechanical vortexing...
More than half a century after the debut of CPM and PERT, we still lack a project scheduling system with calibrated and validated distributions and without requiring complex user input. Modern decision support systems (DSS) for project management are more sophisticated and comprehensive than PERT/CPM. Nonetheless, in terms of stochastic analysis, they show insufficient progress. PERT 21 offers ...
Pancreatic enzyme replacement therapy (PERT) is the only treatment for malabsorption in cystic fibrosis (CF) caused by pancreatic insufficiency (PI). PI occurs in approximately 85% of patients with CF. PERT overcomes some, but not all the signs and symptoms of malabsorption. Clinical parameters such as growth, abdominal pain, diarrhea and gassiness, commonly used to adjust PERT dosing, are show...
In 2006, the US FDA issued a 'Guidance for Industry' regarding submission of New Drug Applications for pancreatic enzyme replacement therapy (PERT) products. Five oral delayed-release PERT products have been approved by the FDA, and several others are under development and/ or evaluation for New Drug Application submission. We present in this paper recommendations of the Cystic Fibrosis Foundat...
PERT is a widely utilized framework for project management. However, as a result of underlying assumptions about the activity times, the PERT formulas prescribe a light-tailed distribution with a constant variance conditional on the range. Given the pervasiveness of heavy-tailed phenomena in business contexts as well as inherently differing levels of uncertainty about different activities, ther...
A β-glucuronidase variant, GUS-TR3337, that was obtained by directed evolution exhibited higher thermostability than the wild-type enzyme, GUS-WT. In this study, the utility of GUS-TR337 as an improved reporter was evaluated. The corresponding gus-tr3337 and gus-wt genes were independently cloned in a plant expression vector and introduced into Arabidopsis thaliana. With 4-MUG as a substrate, p...
BACKGROUND Treatment-naïve patients newly diagnosed with HIV occasionally present with low viral RNA of ≤1'000 copies/ml, raising concerns about viral load underestimation. Because falsely low or undetectable viral loads might lead to inadvertent virus transmission or treatment delays, confirmation of such cases by a sequence-independent viral load test is recommended in Switzerland. METHODS ...
Ensemble classifiers originated in the machine learning community. They work by fitting many individual classifiers and combining them by weighted or unweighted voting. The ensemble classifier is often much more accurate than the individual classifiers from which it is built. In fact, ensemble classifiers are among the most accurate general-purpose classifiers available. We introduce a new ense...
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