Serum immunoglobulin concentrations in 41 children with Perthes' disease and 82 age and sex matched controls were measured by radial immunodiffusion. Significant increases in IgG and IgM were seen in children with Perthes' disease.

BACKGROUND It is known from medical literature that such organisms as Ascaris, Borrelia, Mycoplasma, Toxocara and Toxoplasma can cause arthritis or cause vascular changes. We studied their influence on the incidence, course and outcome of Perthes disease. MATERIALS AND METHODS Sixty-one patients treated for Perthes disease were analysed. Thirty-seven of them took part in a follow-up examinati...

A prospective study was made of 119 children with transient synovitis or any other cause for synovial effusion and elevated intra-articular pressure. During a follow-up of one year not one case of Perthes' disease was diagnosed and the late clinical and radiographic changes were minimal with moderate overgrowth of the femoral head in 33% and widening of the joint space in 14.2%. Our results do ...

Synonyms for this disease include “avascular necrosis of the femoral head” and “aseptic necrosis of the femoral head”, “Perthes disease” and “Legg Perthes” disease, “osteochon-dritis”, “coxae juvenilis”, “coxa plana” and “idiopathic osteosis”. The terms “avascular/aseptic necrosis of the femoral head” are also used to describe a process of femoral head necro-sis in dogs following traumatic frac...

Five atypical cases were observed amongst ninety children with Perthes' disease, ten of whom had bilateral hip joint involvement. All five were boys, four being under 4 years of age. Four had bilateral hip joint disease, four presented with hip pain, three showing some degree of retardation of bone growth. In one case the hip disorder was familial, and in four there were bony abnormalities else...

We treated 98 consecutive patients with Perthes' disease by a unilateral brace in external rotation, flexion and abduction and a further consecutive 110 by a bilateral cast with the hips in internal rotation and abduction. During treatment in the unilateral brace, six (6.1%) hips on the opposite side developed evidence of Perthes' disease and one developed this after the brace had been removed....

We describe a case of a 14-year-old boy with a history of Legg-Calve-Perthes disease diagnosed at the age of 6 years and development of synovial osteochondromatosis of the same hip joint 7 years later. Synovial osteochondromatosis is very rare in children, and to the best of our knowledge, only a single case of Legg-Calve-Perthes disease and secondary synovial osteochondromatosis was described ...

Synonyms for this disease include “avascular necrosis of the femoral head” and “aseptic necrosis of the femoral head”, “Perthes disease” and “Legg Perthes” disease, “osteochon-dritis”, “coxae juvenilis”, “coxa plana” and “idiopathic osteosis”. The terms “avascular/aseptic necrosis of the femoral head” are also used to describe a process of femoral head necro-sis in dogs following traumatic frac...

The literature on Perthes' disease points up the significance of specific anatomical conditions affecting vascularization of the femoral head, as well as immaturity and mechanical weakening of the bone tissue in the etiology and pathogenesis of this disorder in children. An experimental study using calf femurs as models confirmed the author's hypothesis that the areas most susceptible to mechan...

Recent reports have suggested an association between Perthes' disease and an underlying thrombophilic or hypofibrinolytic tendency. In Northern Ireland there is a high incidence of Perthes' disease (11.7 per 100,000 or 1 in 607 children) in a stable paediatric population. We reviewed 139 children with Perthes' disease and compared them with a control group of 220 aged- and gender-matched health...