UNLABELLED Our objective was to compare the diagnostic accuracy of an all-in-one protocol of whole-body 18F-FDG PET/CT and integrated 18F-FDG PET/CT mammography with the diagnostic accuracy of a multimodality algorithm for initial breast cancer staging. METHODS Forty women (mean age, 58.3 y; range, 30.8-78.4 y; SD, 12 y) with suspected breast cancer were included. For the primary tumor, we co...

OBJECTIVE Suspicious incidental gastrointestinal FDG uptake during positron-emission tomography/computed tomography (PET/CT) examinations can be caused by different diseases, including malignancies. However, differentiation with PET alone is difficult. The aim of this study was to investigate the potential of PET alone, contrast-enhanced CT (ceCT), and low-dose CT (ldCT) in routine PET/CT proto...

GE Healthcare, Waukesha, USA A new ToF-PET/MR scanner has recently been deployed at the University Hospital of Zurich for clinical evaluation purposes. The goal of the present work was to compare the image quality obtained on this system with that of equivalent state-of-the-art standalone scanners. The GE Signa PET/MR is a whole-body scanner combining a 3T wide-bore MR system with a 25 cm PET d...

Integrated PET/MR is a newly available imaging technique that includes a simultaneous whole body MR and PET examination Integrated PET/MR avoids co-registration errors in image reconstruction due to differences in patient positioning and has potential for MRI based motion correction to improve registration in the upper abdomen PET/MR is most likely to be advantageous for cancers that are now im...

The synthesis of mellophanic dianhydride (MEDA) from biosourced 1,2,3,4-benzene tetracarboxylic derivatives and its use as a chain extender for mechanically recycled PET (R-PET) an alternative to traditional oil-based pyromellitic (PMDA) is reported. rheological tests performed on the R-PET extruded with MEDA have shown similar results those obtained PMDA, dynamic mechanical thermal analysis (D...

OBJECTIVES To investigate a multimodal, multiparametric perfusion MRI / 18F-fluoro-deoxyglucose-(18F-FDG)-PET imaging protocol for monitoring regorafenib therapy effects on experimental colorectal adenocarcinomas in rats with immunohistochemical validation. MATERIALS AND METHODS Human colorectal adenocarcinoma xenografts (HT-29) were implanted subcutaneously in n = 17 (n = 10 therapy group; n...

OBJECTIVES To test the image quality and feasibility of a sequential low radiation dose protocol for hybrid cardiac PET/CT angiography (CTA). BACKGROUND Multidetector computed tomography (MDCT) is a non-invasive method for coronary angiography. The negative predictive value of MDCT is high but perfusion imaging has a role in detecting functional significance of coronary lesions. This has enco...

OBJECTIVE To correlate the results of (18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) performed with a specific protocol for assessment of breasts with histological/immunohistochemical findings in breast carcinoma patients. MATERIALS AND METHODS Cross-sectional study with prospective data collection, where patients with biopsy-confirmed bre...

UNLABELLED Respiratory motion during PET/CT acquisition can cause misregistration and inaccuracies in calculation of standardized uptake values (SUVs). Our aim was to compare the detection and characterization of thoracic lesions on PET/CT with and without a deep-inspiration protocol. METHODS We studied 15 patients with suspected pulmonary lesions who underwent clinical PET/CT, followed by de...