Studies over the last few decades have demonstrated that the intracellular pH of solid tumors is maintained within a range of 7.0-7.2, whereas the extracellular pH is acidic. A low extracellular pH may be an important factor inducing more aggressive cancer phenotypes. Research into the causes and consequences of this acidic pH of tumors is highly dependent on accurate, precise, and reproducible...

A local pH measurement around cell by pH sensing gel-tool with adhesivecontrollability was developed. We fabricated gel-tool impregnated with pH indicator Bromothymol blue (BTB), which is used for pH measurement in neutral range. Adhesion of the gel-tool to objects such as glass, gel-tool and cell is performed by UV illumination in an electrolyte solution of a certain concentration. Gel-tool is...

Plastic electrodes have been developed for measuring pH in the human gastrointestinal tract. The electrodes have a plastic hydrogen ion sensitive membrane sealed to a length of fluid filled PVC tubing. Two recently developed hydrogen ion sensitive ligands have been examined. Their operational characteristics have been described. These electrodes have an electrical response of 52 to 58 mV/pH uni...

Abstract The phenol red is commonly used in cell culture medium as visual pH indicator by changing its color from darker to the orange-yellowish neutral acidic level. change of hardly be determined using naked eyes that will interpreted differently different person. Thus, this study executed develop a specialized colorimeter for measurement Raspberry Pi microcontroller unit, green LED light sou...