Concerns about the pharmaceutical industry's influence in academic medical centers and on medical education have led many medical schools and teaching hospitals to adopt conflict-of-interest (COI) policies. Although the restrictiveness of these policies differs, the goal is the same: to shield physicians-in-training from the persuasive aspects of pharmaceutical promotion. But do these policies ...

Carbapenem-Resistant Strain of Klebsiella oxytoca Harboring Carbapenem-Hydrolyzing -Lactamase KPC-2 Hesna Yigit, Anne Marie Queenan, J. Kamile Rasheed, James W. Biddle, Antonio Domenech-Sanchez, Sebastian Alberti, Karen Bush, and Fred C. Tenover* Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492; The R. W. Johnson Pharmaceutical Research Institute, Raritan, ...

Pharmacists as one of health-care providers face ethical issues in terms of pharmaceutical care, relationship with patients and cooperation with the health-care team. Other than pharmacy, there are pharmaceutical companies in various fields of manufacturing, importing or distributing that have their own ethical issues. Therefore, pharmacy practice is vulnerable to ethical challenges and needs s...

Historically, academic centers have been the venue for conducting important clinical trials. Teams of welltrained investigators functioning in well controlled settings have set the standard for rigorous scientific design and data interpretation in clinical trials. Institutional review boards have contributed to research subject safety and minimization of scientific misconduct. This system has b...

OBJECTIVE To review original research studies published between 1990 and 2004 on the access and use of medicines in Mexico to assess the knowledge base for reforming Mexico's pharmaceutical policy. MATERIAL AND METHODS A literature review using electronic databases was conducted of original studies published in the last 15 years about access and use of medicines in Mexico. In addition, a manu...

Pharmaceutical marketing has become a mainstay in U.S. health care delivery and traditionally has been directed toward physicians. In an attempt to address potential undue influence of industry and conflicts of interest that arise, states and the recently upheld health care reform act have passed transparency, or "sunshine," laws requiring disclosure of industry payments to physicians. The Cent...

In recent years there has been considerable interest in the synthesis and separation of enantiomers of organic compounds especially because of their importance in the biochemistry and pharmaceutical industry. High-performance liquid Chromatography is a very useful method for the direct separation of enantiomers. However, about 30−40 years ago, commercially available chiral stationary phases wer...