نتایج جستجو برای: phenobarbital

تعداد نتایج: 12577  

Journal: :iranian journal of nuclear medicine 2009
enayatollah nemat khorasani fariba mansouri

introduction: early differentiation of biliary atresia from neonatal hepatitis is of utmost importance, since on time surgery of biliary atresia significantly improves the outcome. hepatobiliary scintigraphy is an integral part of diagnosis work-up of these patients; however its specificity for diagnosis of biliary atresia is suboptimal. in this study we evaluated the value of ursodeoxycholic a...

Background: Hyperbilirubinemiais a common problem in newborn infants. It can progress to kernicterus in severe forms, unless an intervention is initiated. The objective of this study was to compare the efficacy of Clofibrate with Phenobarbital in full-term neonates with nonhemolytic jaundice. Methods: this double blind clinical trial study was performed on 60 neonate who were divided randomly i...

2011
Mahmood Khaksary Mahabady Hossein Najafzadeh Varzi

There are many reports that show the teratogenic effects of phenobarbital can be decreased by stimulation of maternal immune system. Therefore, in this study, the prophylactic effects of levamisole and vitamin E on teratogenic effects of phenobarbital were compared. This study was performed on 20 pregnant rats that were divided into four groups. Control group received normal saline and test gro...

Journal: :Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2001
C M Yokoro S M Pesquero R M Turchetti-Maia J N Francischi M A Tatsuo

The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the abdominal constriction test in mice. Formalin and abdominal constriction tests were the most sensitive procedures for the detection of hyperalg...

Le Quang Thuan Ngo Duc Ngoc Pham Due

Background: Phenobarbital poisoning is common in Vietnam. The aim of this study was to compare the effectiveness of continuous veno-venous hemofiltration (CVVH) and hemodialysis (HD) on clinical outcomes in the treatment of severe acute phenobarbital poisoning. Methods: This was a retrospective observational historically controlled study. 42 patients with severe phenobarbital poisoning were enr...

Enayatollah Nemat Khorasani Fariba Mansouri

  Introduction: Early differentiation of biliary atresia from neonatal hepatitis is of utmost importance, since on time surgery of biliary atresia significantly improves the outcome. Hepatobiliary scintigraphy is an integral part of diagnosis work-up of these patients; however its specificity for diagnosis of biliary atresia is suboptimal. In this study we evaluated t...

Journal: :iranian journal of allergy, asthma and immunology 0
amel chaabane department of pharmacology, university of medicine, monastir, tunisia. najah ben fadhel department of pharmacology, university of medicine, monastir, tunisia. zohra chadli department of pharmacology, university of medicine, monastir, tunisia. nadia ben fredj department of pharmacology, university of medicine, monastir, tunisia. naceur a boughattas department of pharmacology, university of medicine, monastir, tunisia. karim aouam department of pharmacology, university of medicine, monastir, tunisia.

we describe, the first case of phenobarbital-induced dress syndrome presenting as a lichenoïd eruption. a 49-year-old man had received phenobarbital for a cerebral metastasis. twenty-five days later, he developed a purplish skin eruption, odynophagia, oral mucosal erosion and fever. physical examination revealed a cervical lymphadenopathy and facial edema associated to a diffuse violaceous macu...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2003
Ajay Madan Richard A Graham Kathleen M Carroll Daniel R Mudra L Alayne Burton Linda A Krueger April D Downey Maciej Czerwinski Jameson Forster Maria D Ribadeneira Liang-Shang Gan Edward L LeCluyse Karl Zech Philmore Robertson Patrick Koch Lida Antonian Greg Wagner Li Yu Andrew Parkinson

Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular entities as inducers of cytochrome P450 (P450) enzymes. The present study summarizes data obtained from 62 preparations of cultured human hepatocytes that were treated with vehicles (saline or dimethylsulfoxide, 0.1%), beta-naphthoflavone (33 microM), phenobarbital (100 or 250 microM), isoniazid (100 microM) ...

Journal: :Postgraduate Medical Journal 1978

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