INTRODUCTION Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VI...

Photodynamic therapy (PDT) has gained prominence as a non-invasive and selective treatment option for solid tumors non-oncological diseases [...]

photodynamic therapy (pdt) using 5-aminolevulinic acid (5-ala)-induced protoporphyrin ix (ppix) has been considered as a new method for treating neoplasms. however, ala-pdt is suboptimal for thick tumors. searching for new approaches, we investigated the effect of adding differentiation therapy (dt) with vitamin e succinate (ves) to pdt in human prostate ln-cap-fgc10 cancer cells in vitro . the...

BACKGROUND AND OBJECTIVES Photodynamic therapy causes direct cytotoxicity to malignant cells within a tumor. Photodynamic therapy (PDT) can also have both direct and indirect effects upon various non-malignant components of the tumor microenvironment. This action can lead to PDT-mediated angiogenesis and inflammation, which are emerging as important determinants of PDT responsiveness. STUDY D...

Experiments were performed to determine whether the expression and/or repair of potentially lethal damage could be observed in mammalian cells exposed to hemataporphyrin derivative (HPD) photodynamic therapy (PDT). Photodynamic therapy was combined with posttreatment protocols known to inhibit the repair of potentially lethal damage in cells treated with X-rays, ultraviolet radiation, or alkyla...

Photodynamic therapy (PDT), also known as photoradiation therapy, phototherapy, or photochemo therapy, involves the use of a photoactive dye (photosensitizer) that is activated by exposure to light of a specific wavelength in the presence of oxygen. The transfer of energy from the activated photosensitizer to available oxygen results in the formation of toxic oxygen species, such as singlet oxy...

This paper reports the synthesis and photodynamic therapy (PDT) effect of a porphyrin derivative containing tyrosine phosphate, which promises a new, useful approach to develop PDT agents.

BACKGROUND Bumblefoot, referring to bed-sore-like foot lesions, is one of the most important clinical complications in captive birds and has a multifactorial etiology. Photodynamic therapy has been proposed as an alternative treatment for localized infections in response to the escalating problem of antibiotic resistance. The aim of this study was to compare outcomes in a group of captive Sphen...

In article number 2000802 by Xinhui Su, Xiaolian Sun, and co-workers, a 131I labeled ZnPc(COOH)4 conjugated ZnGa2O4:Cr3+ nanoplatform (131I-ZGCs-ZnPcC4) is developed for in vivo radiotherapy (RT) radiation-induced photodynamic therapy (PDT). can not only activate ZGCs long-lasting luminescence which further continuously activates the photosensitizer PDT, but also directly kill cancerous cells. ...