Medicinal plants are resources of new drugs. Phyllanthus niruri L.(Euphorbiaceae) is a widespread tropical herb. The phytochemical screening and quantification of primary metabolites in the plants collected from three geographical locations. Maximum extractive value (3.951%) was found in water extract among test solvents. All metabolites were qualitatively present in water and ethanolic extracts.

Plants can contain a wide variety of substances with antioxidative properties which are associated with important health benefits. These positive health effects are of great importance at a time when the environment is laden with many toxic substances. Five selected herbal plants namely, Mimosa pudica, Phyllanthus niruri, Ceiba pentandra, Eleusine polydactyla and Trema amboinensi, were chosen f...

Phyllanthus niruri L. (Euphorbiaceae) is a well-known hepatoprotective herbal plant. The aim of this study was to investigate the hepatoprotective action of the protein isolate of Phyl-lanthus niruri (P. niruri) against acetaminophen (APAP) induced hepatotoxicity. Protein iso-late of P. niruri was intraperitoneally injected in mice either prior to (preventive) or after the induction of toxicity...

Phyllanthus niruri L., a well-known medicinal plant, has been used as a folk antitumor remedy in the worldwide scale. However, the antitumor components in P. niruri have not been reported. In order to verify the antitumor components of P. niruri and the plants which have the high content of these components, we isolated the antitumor components with bioguided fraction and isolation, by differen...

The main objective of this study is to evaluate the gastroprotective activity of the Phyllanthus niruri leaf extract against ethanol-induced gastric mucosal injury in rats. Six groups of Wistar rats were pretreated, respectively, with distilled water; omeprazole 20 mg/kg; and 250, 500, 750 and 1000 mg/kg P. niruri leaf extract 30 min before oral administration of absolute ethanol to generate ga...

Phyllanthus niruri is an important medicinal plant. To standardize the extract and guarantee its maximum benefit, processing methods optimization ought to be amenable and beneficial. Herein, three dried P. niruri samples, air (AD), freeze (FD) and oven (OD), extracted with various ethanol to water ratios (0%, 50%, 70%, 80% and 100%) were evaluated for their metabolite changes using proton nucle...

In view of the growing interest in Phyllanthus niruri, it was felt necessary to undertake a study of the growth cycle of the herb along with qualitative phytochemical observation in terms of active principle, its distribution in different parts of the plant and effect of storage and the active principle. The main purpose of the study was to develop guidelines for cultivation of the plant, rich ...

The purpose of this study has been the development of an adequate methodology for the quality control of Phyllanthus niruri aqueous extracts. The assay method was tested, with various modifications, to determine its suitability for the quantitative determination of total flavonoids within the crude drug raw material and aqueous extracts. The assay technique for such chemical group is based on t...

Hepatitis B virus (HBV) infection is the leading cause for liver disorders and can lead to hepatocellular carcinoma, cirrhosis and liver damage which in turn can cause death of patients. HBV DNA Polymerase is essential for HBV replication in the host and hence is used as one of the most potent pharmacological target for the inhibition of HBV. Chronic hepatitis B is currently treated with nucleo...