Diabetes mellitus is a chronic hyperglycemic condition with deleterious effects on microcirculation, resulting in diabetic complications. Chronic hyperglycemia induces the generation of reactive oxygen species (ROS), which are the key pathological triggers in the development of diabetic complications. ROS are responsible for the activation of various pathways involved in the genesis of diabetic...

Objective: To evaluate the hepatoprotective potential of methanol extract of roots and rhizomes of Smilax zeylanica L on carbontetrachloride (CCl4) induced hepatotoxicity in Wistar albino rats. Methods: Hepatotoxicity was induced in Wistar albino rats of either sex by administration of CCl4 0.5 ml/kg p.o. once a day for 7 days. The methanol extract of roots and rhizomes of Smilax zeylanica L we...

Medicinal plants have been considered valuable and cheap source of unique phytoconstituents which are used extensively in the development of drugs against various diseases. A large proportion of the world population, especially in the developing countries relies mainly on the traditional system of medicine. The use of plants and plant products in medicines is getting popularized because the her...

As aboriginal sources of medications, medicinal plants are used from the ancient times. Andrographis paniculata is one of the highly used potential medicinal plants in the world. This plant is traditionally used for the treatment of common cold, diarrhoea, fever due to several infective cause, jaundice, as a health tonic for the liver and cardiovascular health, and as an antioxidant. It is also...

BACKGROUND Anethum graveolens Linn., Foeniculum vulgare Mill. and Trachyspermum ammi L. are widely used traditional medicinal plants to treat various ailments. To provide a scientific basis to traditional uses of these plants, their aqueous and organic seed extracts, as well as isolated phytoconstituents were evaluated for their antibacterial potential. METHODS Antibacterial activity of aqueo...

Free radicals are well documented for playing a dual role in our body as both deleterious and beneficial species. In low/moderate concentrations free radicals are involved in normal physiological functions but excess production of free radicals or decrease in antioxidant level leads to oxidative stress. It is a harmful process that can be mediates damage to cell structures, including lipids, pr...

Phytoconstituents have been utilized as medicines for thousands of years, yet their application is limited owing to major hurdles like deficit lipid solubility, large molecular size and degradation in the gastric environment of gut. Recently, phospholipid-complex technique has unveiled in addressing these stumbling blocks either by enhancing the solubilizing capacity or its potentiating ability...

Phytochemical investigation of the ethanolic extract of defatted fruits of Malva sylvestris Linn. (Malvaceae) led to the isolation of six new steroidal lactones and a homomonoterpenic glucoside along with beta-sitosterol-3-beta-D-glucopyranoside. The structures of new phytoconstituents have been elucidated as cholest-5-en-3a-ol-18(21)-olide (sylvestrosterol A), cholest-9(11)-en-3alpha-ol-18(21)...

Objectives: To review the phytoconstituents and pharmacological activities of some common Indian weed plants. Materials and Methods: The information was collected and compiled from scientific literature present in different databases viz., Science Direct, PubMed, MEDLINE, Elsevier and Google Scholar. Results: Literature search revealed that weeds possess diverse group of phytoconstiuents such a...

International Journal of Pharmaceutical Sciences Review and Research Available online at www.globalresearchonline.net © Copyright protected. Unauthorised republication, reproduction, distribution, dissemination and copying of this document in whole or in part is strictly prohibited. © Copyright protected. Unauthorised republication, reproduction, distribution, 7 Sangilimuthu A*, Sathishkumar R,...