BACKGROUND Pityriasis lichenoides (PL) is a lymphoproliferative disease of unknown origin; its diagnosis is based on clinical characteristics and confirmed by histology. OBJECTIVES To describe clinical and histological features of PL in 29 pediatric patients. MATERIALS AND METHODS Retrospective descriptive study of children (patients less than 15 years old) diagnosed with PL between 1986 an...

Febrile Ulceronecrotic Mucha-Habermann disease is a rare and potentially fatal variant of pityriasis lichenoides et varioliformis acuta and is characterized by high fever, constitutional symptoms, and acute oncet of ulceronecrotic lesions. We present an 11-year-old male with Febrile Ulceronecrotic Mucha-Habermann disease who was cured with methotrexate and review the use of methotrexate for thi...

We report a case of a 63-year-old man hospitalized for a polymorphous generalized eruption consisting of maculopapules with peripheral scaling, vesicopustules, and ulceronecrotic and crusted lesions measuring 5-20 mm, localized on his trunk and extremities, particularly exuberant in the flexural area. Histopathology showed necrotic keratinocytes with exocytosis of red blood cells and lymphocyte...

AIM: To report a case of a patient with pityriasis lichenoides et varioliformis acuta (PLEVA) who developed a conjunctival inflammatory nodule. CASE REPORT: a 13-year-old boy with a diffuse papulovesicular rash diagnosed as PLEVA presented to our clinic complaining of irritation in his right eye. Slitlamp examination revealed a conjunctival inflammatory nodule. His symptoms resolved under topic...

A 32-year-old male with febrile ulceronecrotic Mucha-Habermann disease (FUMHD) responsive to methotrexate is reported. This is a severe variant of pityriasis lichenoides et varioliformis acuta characterized by the acute onset of a widespread ulceronecrotic cutaneous eruption together with high fever and systemic involvement. To our knowledge, only 13 patients with FUMHD have been reported to date.

We present a 74-year-old female patient who developed a pityriasis lichenoides chronica (PLC) during etanercept therapy. This association is not described in the literature and might be considered in the spectrum of cutaneous adverse reactions of etanercept.