Numerous Scientists have discovered the procedure of nanotechnology, explicitlynanofibers, asdrug delivery systems for transdermal uses. Nanofibers canbe used to deliver drugs and are capable of controlled release for a continued periodof time. Poly (Lactic Acid) (PLA) is the lastly interesting employed synthetic polymer in biomedical application owing to its well categorized biodegradable prop...

platanus acerifolia, london plane tree, a significant source of airborne allergens, is widely grown in shanghai and other cities in china. in recent decades, little has been known regarding the influence of the allergens on sensitizing the population in the shanghai area. the aims of this study were to purify and characterize the two major allergens and to confirm the immunological activities o...

Plasticized polylactide (PLA) with increased crystallization ability and prolonged life-span in practical applications due to the minimal plasticizer migration was prepared. Branched plasticized PLA was successfully obtained by coupling poly(butylene succinate-co-adipate) (PBSA) to crotonic acid (CA) functionalized PLA. The plasticization behavior of PBSA coupled PLA (PLA-CA-PBSA) and its count...

Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a risk factor of cardiovascular disease. Plasma Lp-PLA₂ is mainly associated with apolipoprotein (apo)B-containing lipoproteins, primarily with low density lipoproteins (LDLs). Importantly, only a proportion of circulating lipoproteins contain Lp-PLA₂. We determined the plasma levels of Lp-PLA₂-bound apoB (apoB/Lp-PLA₂) in patients with prima...

PEG–PLA hydrogels were prepared by stereocomplexation of poly(lactide) (PLA) blocks of opposite chirality. Gelation occurred upon mixing aqueous solutions of both enantiomers of PEG6500–(PLA)2, PEG12500–(PLA)2 and PEG21800–(PLA)8 block copolymers. Stereocomplexed hydrogels from PEG6500–(PLA)2 polymers were found to be stable up to ~37 8C, while those from PEG12500–(PLA)2 and PEG21800–(PLA)8 blo...

Background: The short-time creep behavior for a series of biodegradable nanocomposites which is used as implantable device into body is a crucial factor. In the current paper, we aimed to study the effect of bioactive glass nanoparticles (BGn) on creep and creep-recovery behaviors of PLA/PCL blends at different given load and different applied temperatures. Method: A series of biodegradab...

Background: Platanus species are widely cultured around the world and considered an important cause of allergic reactions. In the present study, we developed a sandwich ELISA to quantify Pla or 3 allergen in P. orientalis pollen extracts grown near high-traffic roads and compared it to pollen extracts collected from rural areas as control. Methods: Pollen samples were collected from three po...

Camptothecin-polylactide conjugates (CMPT-PLA) were synthesized by covalent incorporation of CMPT into PLA of different microstructure, i.e., atactic PLA and atactic-block-isotactically enriched PLA (Pm = 0.79) via urethane bonds. The kinetic release of CPMT from CMPT-PLA conjugates, tested in vitro under different conditions, is possible in both cases and notably, strongly dependent on PLA mic...