background: measuring of maternal serum pregnancy-associated plasma protein-a (papp-a) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta.objective: the aim was to determination of association between placental thickness in second trimester with low level of papp-a in first trimester.materials and methods: in this cohort study, serum papp-a of...

BACKGROUND Measuring of maternal serum pregnancy-associated plasma protein-A (PAPP-A) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta. OBJECTIVE The aim was to Determination of association between placental thickness in second trimester with low level of PAPP-A in first trimester. MATERIALS AND METHODS In this cohort study, serum PAPP-A...

PURPOSE To evaluate morphological and signal intensity (SI) changes of placental insufficiency on magnetic resonance imaging (MRI) and to assess morphological changes and decreased flow voids (FVs) on T2-weighted rapid acquisition with relaxation enhancement (RARE) images for diagnosing placental insufficiency. METHODS Fifty singleton fetuses underwent MRI using a 1.5-T MR scanner. Placental ...

Automobile crashes are the largest cause of death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. Computational models, a useful tool to evaluate the risk of fetal loss in motor vehicle crashes, are limited to quasi-static material properties of the placenta. This study presents a total of 8 dynamic uniaxial tension tests on the full thicknes...

Background: Experiments have shown that opioid drugs abuse during pregnancy can cause a delay in the development of the placenta. In mammals, the placenta is the most important channel for the exchange of Materialss between the maternal and fetal bloods. The present study investigates the time-dependent effect of the addiction duration of maternal morphine consumption during pregnancy. Material...

OBJECTIVE Women previously giving birth with cesarean section have an increased risk of postpartum hemorrhage (PPH) and retained placenta. The objective of this study was to determine if anterior placental location increased the risk of PPH and retained placenta in such women. MATERIALS AND METHODS We performed a prospective cohort study on 400 women with cesarean section delivery in a previo...

BACKGROUND Placenta previa (PP) is an obstetric complication that can affect maternal and fetal morbidity and mortality. Its prevalence is rising due to cesarean sections. There is no quantitative data of placenta in PP. In this study, quantitative parameters of placenta in cases with PP in comparison with normally implanted controls were investigated. METHODS In this quasi experimental study...

OBJECTIVE We sought to apply a standardized evaluation of ultrasound parameters for the prediction of placental invasion in a high-risk population. STUDY DESIGN This was a retrospective review of gravidas with ≥1 prior cesarean delivery who received an ultrasound diagnosis of placenta previa or low-lying placenta in the third trimester at our institution from 1997 through 2011. Sonographic im...

BACKGROUND Rosa damascena, a type of herb, has been used for wound healing in Eastern folk medicine. The goal of this study was to evaluate the effectiveness of rose placenta from R. damascena in a full-thickness wound model in mice. METHODS Sixty six-week-old C57BL/6N mice were used. Full-thickness wounds were made with an 8-mm diameter punch. Two wounds were made on each side of the back, a...

A new method for the taking and embedding of placental blocks to obtain maximum information regarding the uteroplacental vasculature was developed. This method involves taking en face blocks of the basal plate of the placenta. Results show that normal and abnormal maternal vessels are clearly delineated. In addition to conventional full thickness blocks, which provide information about the chor...