Several biological medicines derived from human and animal plasmas can effectively improve haemostasis in individuals with inherited or acquired defects in haemostasis. Factor VIII and factor VIII/vWF and factor IX concentrates are used to treat haemophilia A, von Willebrand disease and hemophilia B respectively. Cryoprecipitates are used to treat hypofibrinogenemia and von Willebrand disease w...

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Iran is a country with advanced health care system. In 1974 government of Iran established a centralized transfusion system. Since then donations of blood may not be remunerated and therapy with blood and its components is free of charge for all Iranian patients in need of the treatment. Most of donors in Iran are educated middle age men. In 2005 Iranian donated more than 1.6 millions units of ...

objective(s): platelet-rich plasma (prp) has recently emerged as a promising strategy in regenerative medicine due to its multiple endogenous growth factors. little is known about the role of prp as a promoter in chondrogenesis of human adipose derived stem cells (hadscs). the aim of this study was to determine whether prp may be considered as a natural and easy achievable source of growth fact...

background: considering the increasing number of patients with hemophilia and infrastructure requirements for a comprehensive approach, development of a recombinant factor has become a milestone. the objective of this study was to assess the safety, efficacy and non inferiority of safacto (recombinant factor viii) compared with plasma-derived factor in the treatment of hemophilia a. methods: 10 ...

abstract background autologus platelet gel is easy to prepare and is relatively low cost. the aim of this study was to prepare and evaluate in vitro efficacy of autologus platelet gel. materials and methods in this experimental study, platelet concentrate and platelet poor plasma were prepared with aphaeresis method. thrombin was prepared by mixing the plasma with calcium. thrombin activity lev...

Traditional medicines are used by approximately 60 per cent of the world's population. These are used for primary health care not just in rural areas of developing countries, but also in developed countries where modern medicines are predominantly used. While traditional medicines are derived from plants, minerals, and organic matter, the herbal drugs are prepared exclusively from medicinal pla...