objective(s): gentamicin is used for the treatment of gram-negative bacterial infections. however, gentamicin administration is limited because of nephrotoxicity. the aim of the present study was to evaluate the protective effect of crocin against gentamicin-induced nephrotoxicity in rats. materials and methods: thirty two male wistar rats received gentamicin (100 mg/kg, ip), with or without cr...

Dry matter intake, nitrogen intake, nitrogen digestibility, rumen ammonia-N and plasma urea-N concentration were measured in young rusa deer fed 4 diets containing 90 to 205 g/kg DM crude protein. The level of crude protein associated with maximal voluntary food intake and dry matter digestibility for these animals was found to be about 160 g/kg DM. Plasma urea-N was positively related to rumen...

WELBOURNE, TOMAS C. Influence of chronic acidosis on plasma glutamine and urea production in the nephrectomized rat. Am. J. Physiol. 224(4) : 796-802. 1973.-Nitrogen partition between glutamine and urea production in normal and chronic acidosis was investigated in bilaterally nephrectomized rats. Metabolic acidosis was induced by chronic administration of NH&l in one group and by administration...

Hepatic urea synthesis is the organism's main channel for the disposal of nitrogen and it may be an 'essential' liver function. In six control subjects and five patients with cirrhosis of the liver urea synthesis was studied during continuous infusion for six to 24 hours of about 3 mmol alpha-amino nitrogen/h X kg body weight. The urea synthesis rate was calculated in intervals of two hours as ...

Hypertonic solutions play an important role in the treatment of tissue edema. Following the induction of experimental vasogenic brain edema by occlusion of the common carotid arteries in eight rabbits, the effect of hypertonic lactated Ringer's solution (subjects), vs. isotonic lactated Ringer's solution (control), was studied on blood pressure, electrolyte (sodium, potassium, and calcium) ...

An experiment was conducted to determine the relationship between nitrogen intake and testicular urea content. Twenty ram lambs of fat-tailed Iranian native breed were used in this study. The mean (±SD) age and body weight of the lambs were 180±20 days and 36.7±6.3 kg, respectively. The lambs were divided in to five groups of equal size, and received a ration containing a single protein source;...

The objective of this review is to describe recent research findings related to the use of milk or blood urea nitrogen to identify inefficiencies in protein nutrition and estimate nitrogen excretion. A mathematical model was developed to integrate milk urea nitrogen (MUN) and milk composition to predict urinary and fecal excretion, intake, and utilization efficiency for nitrogen in lactating da...

Hyperlipidic diets limit glucose oxidation and favor amino acid preservation, hampering the elimination of excess dietary nitrogen and the catabolic utilization of amino acids. We analyzed whether reduced urea excretion was a consequence of higher NO x ; (nitrite, nitrate, and other derivatives) availability caused by increased nitric oxide production in metabolic syndrome. Rats fed a cafeteria...