Therapeutic plasma exchange is an extra-corporeal technique able to remove from blood macromolecules and/or replace deficient plasma factors. It is the treatment of choice in hyperviscosity syndrome, due to the presence of quantitatively or qualitatively abnormal plasma proteins such as paraproteins. In spite of a general consensus on the indications to therapeutic plasma exchange in hypervisco...

The effects of plasma exchange using a low viscosity plasma substitute on blood viscosity and cerebral blood flow were investigated in eight subjects with normal cerebral vasculature. Plasma exchange resulted in significant reductions in plasma viscosity, whole blood viscosity, globulin and fibrinogen concentration without affecting packed cell volume. The reduction in whole blood viscosity was...

Erythrocytes and plasma proteins contribrelated (p < 0.001) with the plasma ute to viscosity of blood. Therefore, blood macroglobulin concentration in g/100 ml. viscosity was measured in 16 persons with The plasma of patients with macroglobumacroglobulinemia with a cone-plate vislinemia is a non-Newtonian fluid, but at a cometer at defined shear rates. In each given shear rate the plasma viscos...

Erythrocytes and plasma proteins contribrelated (p < 0.001) with the plasma ute to viscosity of blood. Therefore, blood macroglobulin concentration in g/100 ml. viscosity was measured in 16 persons with The plasma of patients with macroglobumacroglobulinemia with a cone-plate vislinemia is a non-Newtonian fluid, but at a cometer at defined shear rates. In each given shear rate the plasma viscos...

Increases in the viscosity of blood and plasma predict clinical manifestations of atherothrombotic vascular disease. The clinical utility of viscosity measurements in cardiovascular risk factor analysis requires reference values established from a healthy disease-free population. A cohort of 126 (71 men, 55 women) healthy nonsmoking adults had fasting blood analysis after a 12-14-h fast. Viscos...

We hypothesized that the response of cerebral blood flow (CBF) to changing viscosity would be dependent on "baseline" CBF, with a greater influence of viscosity during high-flow conditions. Plasma viscosity was adjusted to 1.0 or 3.0 cP in rats by exchange transfusion with red blood cells diluted in lactated Ringer solution or with dextran. Cortical CBF was measured by H(2) clearance. Two group...

AIMS To assess the relation of plasma viscosity to disease activity in patients with inflammatory bowel disease. METHODS Crohn's disease (n = 60) and ulcerative colitis (n = 71) were diagnosed on the basis of typical histological or radiological features. Active Crohn's disease was defined as a Crohn's disease activity index of 150 or over. Active ulcerative colitis was defined as a liquid st...

semen hyperviscosity (shv) is one of the factors involved in deficiency in sperm function. this research aimed to evaluate seminal plasma total antioxidant capacity (tac) and malondialdehyde (mda) levels in infertile patients with hyperviscous and non-hyperviscous semen samples to understand whether hyperviscous semen is associated with oxidative damage in infertile subjects. in this cross sect...

Certain factors are common to the erythrocyte sedimentation rate and the plasma viscosity. Thus fibrinogen increases the erythrocyte sedimentation rate (Gram, 1921 ; Greisheimer, Johnson, and Ryan, 1929) and Hardwicke, Ricketts, and Squire (1950) found that a direct logarithmic relation exists between the erythrocyte sedimentation rate and the plasma fibrinogen concentration. Also fibrinogen ex...