نتایج جستجو برای: platelet endothelial cell adhesion molecule

تعداد نتایج: 1952900  

Journal: :American journal of physiology. Cell physiology 2004
Peter J Kuhlencordt Eva Rosel Robert E Gerszten Manuel Morales-Ruiz David Dombkowski William J Atkinson Fred Han Frederic Preffer Anthony Rosenzweig William C Sessa Michael A Gimbrone Georg Ertl Paul L Huang

The objective of this study was to determine whether absence of endothelial nitric oxide synthase (eNOS) affects the expression of cell surface adhesion molecules in endothelial cells. Murine lung endothelial cells (MLECs) were prepared by immunomagnetic bead selection from wild-type and eNOS knockout mice. Wild-type cells expressed eNOS, but eNOS knockout cells did not. Expression of neuronal ...

2011
Malgorzata Graczyk Zbigniew Bartuzi Michal Przybyszewski Katarzyna Napiórkowska Magdalena Zbikowska-Gotz Jacek Muæka Ewa Szynkiewicz Robert Zacniewski Ewa Socha

Introduction PECAM-1 (CD31) (Platelet Endothelial Cell Adhesion Molecule-1) is an adhesive molecule found on the side surfaces of endothelial cells and blood platelets, taking part in the cell adhesion processes. Adhesive molecules are known to play an important part in the inflammatory processes, including inflammations with allergic background. The goal of the study was to assess the sEselect...

Journal: :Hypertension 2011
Piyali Chatterjee Valorie L Chiasson Shelley E Kopriva Kristina J Young Victor Chatterjee Kathleen A Jones Brett M Mitchell

Preeclampsia may result from overactivation of the maternal immune system and is characterized by endothelial dysfunction and excessive inflammation. Given the importance of maternal immune system regulation and anti-inflammatory cytokines in normotensive pregnancies, we hypothesized that maternal immune system activation via Toll-like receptor 3 during pregnancy would cause preeclampsia-like s...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2008
Myron I Cybulsky

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a complex adhesion and signaling molecule expressed by endothelial cells, platelets, and leukocytes.1,2 On endothelial cells this transmembrane glycoprotein member of the immunoglobulin gene superfamily is concentrated at intercellular junctions and cycles through vesicle-like structures contiguous with the lateral plasma membrane...

Journal: :acta medica iranica 0
mehdi farzadnia department of pathology, school of medicine, mashhad university of medical sciences, mashhad, iran. hossein ayatollahi department of hematopathology and blood banking; school of medicine, mashhad university of medical sciences, mashhad, iran. maliheh hasan zade department of obstetrics and gynecology, school of medicine, mashhad university of medical sciences, mashhad, iran. mohammad hadi sadeghian department of hematopathology and blood banking; school of medicine, mashhad university of medical sciences, mashhad, iran. naser tayebi meybodi department of pathology, school of medicine, mashhad university of medical sciences, mashhad, iran.

endothelial dysfunction is thought to be a central pathogenic feature in preeclampsia on the basis of elevated adhesion molecules. soluble forms of these molecules can be detected in plasma, and their concentrations are thought to reflect the degree of activation of a particular cell type. the aim of the present study was to compare the levels of soluble vascular cell adhesion molecule-1 (svcam...

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