a 19-year-old girl referred to our clinic complaining of a painless lump on the left side of her tongue.  the patient had no history of dysphagia, lingual paresthesia or bleeding. physical examination revealed the presence of multiple enlarged lymph nodes on the left side of her neck.  histopathology of lingual mass and lymph nodes showed pleomorphic adenoma.  to our knowledge, this is the firs...

OBJECTIVE This study aimed to characterize alteration in the immunohistochemical expression of pRb in normal tissue of the salivary gland surrounding pleomorphic adenoma, the tumor cells of pleomorphic adenomas, and carcinoma arising in pleomorphic adenoma. STUDY DESIGN A selected series of 29 cases of pleomorphic adenomas, and 27 cases of carcinoma ex-pleomorphic adenoma (undifferentiated an...

Background: Carcinoma ex pleomorphic adenoma is an exceedingly rare neoplasm of the submandibular gland with an overall poor prognosis. Metastatic deposits of carcinoma ex pleomorphic adenoma are either composed exclusively of malignant elements or contain mixed benign and malignant components. Case Presentation: We describe the case of a 63-year-old male with a carcinoma ex pleomorphic adenoma...

A 19-year-old girl referred to our clinic complaining of a painless lump on the left side of her tongue.  The patient had no history of dysphagia, lingual paresthesia or bleeding. Physical examination revealed the presence of multiple enlarged lymph nodes on the left side of her neck.  Histopathology of lingual mass and lymph nodes showed pleomorphic adenoma.  To our knowledge, this is the firs...

Immunohistological expressions of the cytokeratin (CK) subclass, vimentin, glial fibral antigen protein (GFAP), alpha-smooth muscle actin, and S-100 protein were investigated in pleomorphic adenoma of the parotid gland. In addition, the correlation between immunohistological findings in the normal parotid gland and those in pleomorphic adenoma was examined. Vimentin, S-100 protein, and GFAP, wh...

salivary gland tumors are rare in children and, when they do arise, they mainly affect the major salivary glands. minor salivary gland tumors are rare in children and are responsible for less than 10% of the cases. pleomorphic adenoma is the most common tumor of the salivary glands. the most common sites of pleomorphic adenoma of the minor salivary glands are the palates, followed by the lips a...

Pleomorphic adenoma is the most common benign tumour of major salivary gland presenting as a painless mass gradually increasing in size, usually involving parotid gland. In minor gland, it more palate. lip rare tumour. Thus, we present case pleomorphic originating from upper 75 years old male patient. The tumor was completely excised and sent for histopathological examination which showed micro...

sarcomas account for less than 1% of all primary breast malignancies, pleomorphic sarcoma of the breast being even rarer. we present two cases of pleomorphic sarcoma of the breast in a 35-year-old and a 43-year-old female. an extensive review of the available literature with evaluation of the etiology, changing terminologies and histopathologic features of pleomorphic sarcoma of the breast are ...

INTRODUCTION Pleomorphic adenoma accounts for 65 percent of all salivary gland tumors. It has been identified in several anatomical regions, but pleomorphic adenoma arising in the ear canal, first described in 1951, is extremely rare. CASE PRESENTATION A 40-year-old Japanese man's left ear canal was obstructed by a pleomorphic adenoma that caused mild conductive hearing loss. The tumor was re...

Pleomorphic adenoma is a benign tumor of the salivary glands, most commonly affecting the parotid gland. Pleomorphic adenoma of the ear is rare. The use of imaging modalities, especially magnetic resonance imaging (MRI), is particularly useful in localizing and surgical planning of these tumors. We present a case of pleomorphic adenoma invading the mastoid cortical bone, with review of literature.