Reconstruction of extracellular matrix substrates for delivery of functional photoreceptors is crucial in pathologies such as retinal degeneration and age-related macular degeneration. In this study, we assembled polyelectrolyte films using the layer-by-layer deposition method. The buildup of three different films composed of poly(L-lysine)/chondroitin sulfate (PLL/CSA), poly(L-lysine)/poly(sty...

The ability of guinea pigs to recognize poly-I,-lysine (PLL), and hapten conjugates of PLL (H-PLL) as antigens is under the control of a single autosomal dominant gene which we will refer to as the PLL gene (1-3). Responder animals carrying this gene form specific antihapten antibodies and display delayed hypersensitivity reactions after immunization with H-PLL conjugates such as 2,4-dinitrophe...

STUDY DESIGN The clinical and radiologic results of the patients with removed posterior longitudinal ligament (PLL) were compared with those of the patients with preserved PLL in the treatment of cervical spondylotic myelopathy (CSM). OBJECTIVE To investigate effect of resection of the PLL in anterior decompression for CSM. SUMMARY OF BACKGROUND DATA Anterior decompression has been proved t...

In a classical PLL, the phase detector (PD) and charge pump (CP) noise is multiplied by N, when referred to the VCO output, due to the divide-by-N in the feedback path. It often dominates the in-band phase noise and limits the achievable PLL jitter·power Figure-Of-Merit (FOM). A subsampling PLL uses a PD that sub-samples the high frequency VCO output with the reference clock. The PD and CP nois...

In a classical PLL, the phase detector (PD) and charge pump (CP) noise is multiplied by N, when referred to the VCO output, due to the divide-by-N in the feedback path. It often dominates the in-band phase noise and limits the achievable PLL jitter•power Figure-Of-Merit (FOM). A sub-sampling PLL uses a PD that sub-samples the high frequency VCO output with the reference clock. The PD and CP noi...

background: the magnetic nanoparticle-based transfection method is a relatively new technique for delivery of functional genes to target tissues. we aimed to evaluate the transfection efficiency of rat neural stem cell (nsc) using poly-l-lysine hydrobromide (pll)-coated super paramagnetic iron oxide nanoparticles (spion). methods: the spion was prepared and coated with pll as transfection agent...

Background. The expression term of the gene transfected in cells needs to belong enough inorder to make a gene therapy clinically effective. The controlled release of the transfected gene can be utilized. The new biodegradable hydrogel material created by 20 w/w% aldehyded dextran and 10 w/w% ε -poly(L-lysine) (ald-dex/PLL) was developed. We examined whether it could be as a nonviral carrier of...

| This paper presents a salient method to nd an optimal bandwidth for low noise phase-locked loop (PLL) applications by analyzing a discrete-time model of charge-pump PLLs based on ring oscillator VCOs. The analysis shows that the timing jitter of the PLL system depends on the jitter in the ring oscillator and an accumulation factor which is inversely proportional to the bandwidth of the PLL. F...

background: the microarray technology is in needed of cost-effective, low background noise and stable substrates for successful hybridization and analysis. methods: in this research, we developed a three-dimentional stable and mechanically reliable microarray substrates by coating of two polymeric layers on standard microscope glass slides. for fabrication of these substrates, a thin film of ox...

The feasibility of constructing polymer/clay nanocomposites with polypeptides as the matrix material is shown. Cationic poly-L-lysine HBr (PLL) was reinforced by sodium montmorillonite clay. The PLL/clay nanocomposites were made via the solution-intercalation film-casting technique. X-ray diffraction and transmission electron microscopy data indicated that montmorillonite layers intercalated wi...