poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. the virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. initial symptoms of polio include ...

Further evidence of the extensive effects of infection with the poliomyelitis virus upon many bodily systems is presented in this paper, the second of a series (1) describing metabolic and physiological features of the natural course of paralytic acute anterior poliomyelitis during its acute, convalescent and chronic phases. The most marked alteration in metabolism noted during the immobilizati...

The inhibition of multiplication of one poliomyelitis virus by a poliomyelitis virus of another immunologic type has been established by using tissue cultures of monkey testes. The degree of interference varied from none, to partial, to complete, depending upon the time between inoculation of the interfering and the challenge viruses, and the amount of each virus inoculated. Reciprocal interfer...

Wild poliovirus-associated paralytic poliomyelitis has not been reported in Australia since 1977. We report type 1 wild poliovirus infection in a man who had traveled from Pakistan to Australia in 2007. Poliomyelitis should be considered for patients with acute flaccid paralysis or unexplained fever who have been to poliomyelitis-endemic countries.

1. An instance of successful inoculation of poliomyelitis virus after preservation for 8 years in 50 per cent glycerol is reported. 2. The virulence of the material injected remained essentially unchanged during this period. 3. The fact that poliomyelitis virus will survive in glycerol for so great a period may be taken as further indication of the improbability of streptococci as the inciting ...

BACKGROUND The international spread of wild poliomyelitis outbreaks continues to threaten eradication of poliomyelitis and in 2014 a public health emergency of international concern was declared. Here we describe a risk scoring system that has been used to assess country-level risks of wild poliomyelitis outbreaks, to inform prioritisation of mass vaccination planning, and describe the change i...

BACKGROUND Nigeria is one of the major African countries in which incidences of polio infection persist in spite of several eradication efforts. The preponderance of paralytic poliomyelitis particularly in the northern part of Nigeria raises the question as to whether parents of children affected with polio know how polio is contracted and spread, whether having a disabled child affects the par...

The abrupt transition to heightened poliomyelitis epidemicity in England and Wales, 1947-1957, was associated with a profound change in the spatial dynamics of the disease. Drawing on the complete record of poliomyelitis notifications in England and Wales, we use a robust method of spatial epidemiological analysis (swash-backwash model) to evaluate the geographical rate of disease propagation i...

the development and widespread use of a prophylactic vaccine significantly reduced the incidence of poliomyelitis. at present we more commonly encounter with poliomyelitis sequelae especially in developing countries. we evaluate the results of a modified innominate osteotomy for leg length discrepancy in poliomyelitis. instead of triangular bone graft as in salter’s innominate osteotomy , a tra...