The synthesis and properties of hybrid poly(ε-caprolactone) (PCL)–poly(ethylene oxide) (PEO) covalent adaptable networks have been investigated.

Objectives We aimed to develop a sustained release system for an anti-TNFa drug in treatment of chronic inflammatory arthritis. A novel form of intra-articularly injectable etanercept (ETN) loaded poly(ε-caprolactone) (PCL) or methoxy poly(ethylene glycol)-poly(ε-caprolactone)methoxy poly(ethylene glycol) (MPEG-PCL-MPEG) microspheres (patent pending) were prepared to provide long term controlle...

Partitioning oracles were introduced by Hassidim et al. (FOCS 2009) as a generic tool for constant-time algorithms. For any ε > 0, a partitioning oracle provides query access to a fixed partition of the input bounded-degree minor-free graph, in which every component has size poly(1/ε), and the number of edges removed is at most εn, where n is the number of vertices in the graph. However, the or...

The random architecture of a commercial copolymer of poly(DL-lactic acid) and poly(ε-caprolactone), poly(DL-lactide-co-caprolactone), has been characterized by chemical structure analysis from hydrogen-1 nuclear magnetic resonance results. Moreover, spherical nanodomains have been detected in the thin films of this copolymer obtained after solvent evaporation. These nanodomains studied by atomi...

A new well-defined bisbenzoin group end-functionalized poly(ε-caprolactone) macrophotoinitiator (PCL-(PI)2) was synthesized by combination of ring opening polymerization (ROP) and click chemistry. The ROP of ε-CL monomer in bulk at 110 °C, by means of a hydroxyl functional initiator namely, 3-cyclohexene-1-methanol in conjunction with stannous-2-ethylhexanoate, (Sn(Oct)2), yielded a well-define...

We consider the following clustering with outliers problem: Given a set of points X ⊂ {−1, 1}, such that there is some point z ∈ {−1, 1} for which Prx∈X [〈x, z〉 ≥ ε] ≥ δ, nd z. We call such a point z a (δ, ε)-center of X. In this work we give lower and upper bounds for the task of nding a (δ, ε)-center. Our main upper bound shows that for values of ε and δ that are larger than 1/poly log(n), th...