the association of secreted frizzled related protein type 4 (sfrp4) as an antagonist of wnt mole-cules in apoptotic events has been reported previously. moreover, its increased expression has been reported in the ovary of women with polycystic ovary (pco). we have demonstrated in-creased sfrp4 in pco-induced rat ovary related to an increased number of apoptotic follicles showing nuclear ?cateni...

Objective Polycystic ovary syndrome is a frequent condition in women of reproductive age with prevalence rate of 5-10%. This study purposed to determine the relationship between polycystic ovary syndrome and the outcome of assisted reproductive treatment (ART) cycle in Tehran, Iran. MaterialsAndMethods In this historical cohort study, 996 infertile women were included in the study between Janua...

CONTEXT Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count. OBJECTIVE Does Anti-Mullerian Hormone reflect antral follicle count similarly in women with or without polycystic ovary syndrome or polycystic ovarian morphology? DESIGN Cross-sectional, case-control. SETTING Women who delivered preterm in 19...

background and objective: the effect of opioids on the reproductive system has been studied as an attractive research field. in this study, the effect of morphine as an analgesic opioid was evaluated on the ovarian polycystic induction in the rat. materials & methods: in this study, 24 female virgin wistar rats weighing 200-250 g were injected with morphine (1-10 mg/kg/day) for 9 days. cont...

45 female patients with polycystic ovary syndrome took thioctic acid (Thioctacid-HR), 600 mg (n = 25) or high protein diet (n = 20). Fast insulin and glucose stimulus insulin were investigated before and after 3 months taken treatment. The use of thioctic acid, 600 mg is a new effective pathogenetics therapy of polycystic ovary syndrome on influence of hyperinsulinemia, HOMA-IR index and ovary ...

In the past, polycystic ovary syndrome has been looked at primarily as an endocrine disorder. Studies now show that polycystic ovary syndrome is a metabolic, hormonal, and psychosocial disorder that impacts a patient's quality of life. It is extremely important to holistically treat these patients early on to help them deal with the emotional stress that is often overlooked with polycystic ovar...

BACKGROUND Polycystic ovary syndrome is the most frequently seen endocrine disorder in women of reproductive age with a prevalence of about 10%. AIMS To investigate the efficiency of growth differentiation factor 9 and bone morphogenetic protein 15 during folliculogenesis in a dehydroepiandrosterone-induced mouse Polycystic ovary syndrome model. STUDY DESIGN Animal experimentation. METHOD...

background: the purpose of the study was to examine whether patients with subclinical hypothyroidism (sch) should be excluded before making a diagnosis of polycystic ovary syndrome (pcos). methods: seven hundred sixteen patients, 462 with true pcos, 31 with pcos-sch, and 223 normal cycling women were enrolled. clinical, metabolic, and hormonal parameters among the groups were investigated. cont...

COMPUTATIONAL BIOLOGY APPROACHES AND BIOINFORMATICS TO IDENTIFY KEY GENES IN POLYCYSTIC OVARY SYNDROME: A SYSTEMATIC REVIEW