HIV and AIDS patients are susceptible to opportunistic infections. Oral candidiasis or thrush is the primary manifestation of fungal infection in these patients. The objective this literature review was summarize established novel treatment options for oropharyngeal infections HIV/AIDS Azoles polyenes two antifungal drug classes employed oral candidiasis. A conducted on Medline Google Scholar O...

The suggestion of Zechmeister (1) that phytofluene might be a precursor of lycopene has been expanded by Porter and Lincoln (2), who proposed on the basis of experiments with tomatoes that a successive dehydrogenation of more saturated polyenes’ leads to the biosynthesis of lycopene and other carotenoids. This sequence would involve the intermediary formation of tetrahydrophytoene, phytoene, ph...

We have developed procedures for synthesizing dimethyl polyenes using living polymerization techniques and have initiated investigations of the spectroscopic properties of these molecules. Purification using high-performance liquid chromatography (HPLC) of the polyene mixtures resulting from the syntheses promises to provide all-trans polyenes with a wide range in the number of conjugated doubl...

Steady-state and ultrafast transient absorption spectra were obtained for a series of conformationally constrained, isomerically pure polyenes with 5-23 conjugated double bonds (N). These data and fluorescence spectra of the shorter polyenes reveal the N dependence of the energies of six (1)B(u)(+) and two (1)A(g)(-) excited states. The (1)B(u)(+) states converge to a common infinite polyene li...

Based on the total π-electron energies Eπs of Hückel Molecular Orbital (HMO) method for all the possible isomers of conjugated acyclic polyenes (C₂nH₂n+2) up to n = 7, the structure-stability relation of the possible isomers was analyzed. It was shown that the mean length of conjugation L can roughly predict the ordering of stability among isomers, while the Z-index, or Hosoya-index, can almost...