post transcriptional regulation

Objective(s):OCT4 is a transcription factor required for pluripotency during early embryogenesis and the maintenance of identity of embryonic stem cells and pluripotent cells. Therefore, the effective expression regulation of this gene is highly critical. UTR regions are of great significance to gene regulation. In this study, we aimed to investigate the potential regulatory role played by 5´UT...

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cellular response to ionizing radiation: a microrna story

Journal: :international journal of molecular and cellular medicine 0

mohammad halimi department of biology, faculty of sciences, university of guilan, rasht, iran.سازمان اصلی تایید شده: دانشگاه گیلان (guilan university) mohsen asghari department of biology, faculty of sciences, university of guilan, rasht, iran.سازمان اصلی تایید شده: دانشگاه گیلان (guilan university) reyhaneh sariri department of biology, faculty of sciences, university of guilan, rasht, iran.سازمان اصلی تایید شده: دانشگاه گیلان (guilan university) dariush moslemi department of radiation oncology, babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences) hadi parsian cellular and molecular biology research center, babol university of medical sciences, babol, iran.سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (babol university of medical sciences)

micrornas (mirnas) represent a class of small non-coding rna molecules that regulate gene expression at the post-transcriptional level. they play a crucial role in diverse cellular pathways. ionizing radiation (ir) is one of the most important treatment protocols for patients that suffer from cancer and affects directly or indirectly cellular integration. recently it has been discovered that mi...

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