background dox is a powerful chemotherapeutic agent used in the treatment of solid tumors and malignant hematological diseases. however, its cardiac toxicity limits the clinical usefulness of this drug. previous reports have shown corticosteroids induce a cytoprotective effect on cardiomyocytes. mouse transgenic embryonic stem cell-derived pure cardiomyocytes may be considered as a model for as...

background the ability to follow the distribution and migration of biologically active cells in human is essential for the development of cell-based therapies and diagnostics. nuclear medicine imaging is widely applied in clinic as an attractive technique for in vivo wbc and stem cell tracking. the aim of this study was to evaluate prosthesis infection of a 51 years old man with previous histor...

background the aim of this clinical trial was the assessment of safety and efficacy of submocosal and periurethral injections of peripheral blood derived autologous stem cells along with platelets, and focused on outcome for six months. methods an open, prospective study was conducted on 10 patients presenting with stress urinary incontinence. at the baseline (pre-operative), 1, 3 and 6 months ...

stem cells are cells with the ability to divide for indefinite periods and to give rise to specialized cells.  stem cell therapy has now been emerged as an extraordinary promise to treat a wide range of diseases and conditions.  however, except blood stem cell transfer by bone marrow transplant which has been used as an standard practice for more than 50 years, nearly all of therapeutic potenti...

introduction: sharply progression and development in different aspect of technology and science in the field of medicine and sanitation bring many challenges in biological moral and social aspects of the life. meanwhile statistical problems of this subjects will be rised. study and researches on embryonic stem cells are one of this specimens. religions and different ideological views in vast hu...

introduction: gold standard for alveolar cleft bone grafting is autogenous bone. advantage of adding the growth factors to the bone is established, so adding prf to the autogenous bone may have beneficial effects. methods:  platelet-rich plasma admixed with autogenous bone and as a biologic membrane over the bone grafted alveolar cleft was used. results:  autogenous bone in all (four cases) was...

introduction based on previous researches, dental pulp stem cells (dpscs) are easily accessible with limited morbidity after collection. their embryonic origin, from neural crests, explains their multipotency. dpscs are primarily derived from the pulp tissues of the teeth.objective: this study was undertaken to isolate, culture, and characterize two different third molar and first premolar huma...

background  many biomaterials are used during the open sinus lift surgery, beneath the elevated scheniderian membrane and maxillary sinus bony floor but the search for ideal material continues. methods  in the maxillary posterior atrophic ridges with the bone height less than four millimeters the open sinus lift surgery performed. the autologous platelet-rich plasma (prf) was used as the sole g...

background stem cell transplantation has become as a novel treatment  for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. improved survival of transplant recipients has raised awareness of post-transplant complications. one of these complications is transplant-related osteoporosis. methods  in this manuscript we review prevention methods for transplant-related ...

background cancer stem cells play crucial roles in resistance to therapeutic schemes and relapse of disease, so it is important to find targeted therapies that kill them selectively. breast cancer is the most common cancer in females living in all part of the world including iran and it has an important burden in public health with direct impact on patients’ families. breast cancer in young adu...