I mprovements in techniques, instrumentation, and intraocular lens design appear to have been associated with declining rates of posterior capsule opacification following cataract surgery. While morbidity associated with posterior capsule opacification and its treatment, Nd:YAG laser capsulotomy, is limited, progressive opacification affects quality of vision and visual function, while capsulot...

OBJECTIVE To present a new model of posterior capsule opacification (PCO) in mice. METHODS An extracapsular lens extraction was performed in 28 consecutive mice. Animals were humanely killed 0 and 24 hours and 3 and 14 days after surgery. Eyes were enucleated and processed for light microscopy and immunohistochemistry. RESULTS In 20 animals (71%), the eye appeared well healed before death. ...

OBJECTIVE To evaluate the effectiveness of various surgical procedures in the management of posterior capsule and anterior vitreous on the prevention of visual axis opacification. SUBJECTS, MATERIAL AND METHODS We retrospectively reviewed 120 eyes operated for unilateral congenital cataracts, with a median age at the time of cataract surgery of 21 months (interquartile range, 6-52 months). Th...

Objective To evaluate intraocular scattering in eyes with posterior capsule opacification by means of an objective scatter index (OSI) obtained from double-pass images of optical quality assessment system (OQAS TM II) and to determine the indication for laser capsulotomy when patients report visual disturbances without decreased visual acuity. Methods In this prospective, observational, and n...

PURPOSE To investigate the relative merit of retroillumination and of reflected light slit-lamp-derived photographs in the assessment of the opacification of the posterior lens capsule. METHODS Retroillumination and slit-lamp-derived reflected-light photographs were taken on 23 consecutive eyes with posterior capsule opacification (PCO) in uncomplicated pseudophakia. Subjective grading was pe...

A Nd:YAG laser photodisruption is a wellestablished tool for intraocular surgery, such as treatment of posterior capsule opacification that affects the visual function. During the intraocular procedure, called laser capsulotomy, the excitation pulse is focused several times just behind the posterior capsule and intraocular lens to create the central opening in the opacified capsule. We built an...

Posterior capsule opacification (PCO) is the most common complication of cataract surgery. It causes a gradual deterioration visual acuity, which would otherwise improve after successful procedure. Despite recent advances in ophthalmology, this has not been eradicated, and incidence PCO can be as high 10%. This article reviews literature concerning pathomechanism examines biochemical pathways i...